HitPredict

Interactor 1: FXL16 (A2RT62)
F-box/LRR-repeat protein 16 (F-box and leucine-rich repeat protein 16)
Gene: Fbxl16

Interactor 2: SKP1 (Q9WTX5)
S-phase kinase-associated protein 1 (Cyclin-A/CDK2-associated protein p19) (S-phase kinase-associated protein 1A) (p19A) (p19skp1)
Gene: SKP1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	24390425
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 479 Mm			1 163
+	Hs
		928985 FXL16_HUMAN (1-479): 4.28e-77: 250: 96.45		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Mm
		1206354 FXL21_MOUSE (41-413): 6.23e-47: 169: 13.57		SKP1_MOUSE (1-163): 3.56e-91: 263: 100.00
+	At
		1123017 TIR1_ARATH (92-479): 3.54e-59: 206: 19.33		ASK4_ARATH (4-162): 1.96e-75: 223: 52.80
+	At
		1123022 TIR1_ARATH (92-479): 3.54e-59: 206: 19.33		ASK3_ARATH (4-162): 9.49e-74: 219: 50.31
+	At
		1107590 TIR1_ARATH (92-479): 3.54e-59: 206: 19.33		SKP1A_ARATH (3-162): 6.66e-73: 217: 57.76
+	At
		1123015 TIR1_ARATH (92-479): 3.54e-59: 206: 19.33		SKP1B_ARATH (3-162): 3.47e-71: 213: 55.56
+	At
		221642 TIR1_ARATH (92-479): 3.54e-59: 206: 19.33		ASK11_ARATH (4-162): 3.36e-71: 213: 55.35
+	Hs
		929092 FXL17_HUMAN (128-478): 1.75e-39: 153: 15.36		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Hs
		929099 FBXL7_HUMAN (204-479): 4.77e-40: 152: 23.31		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	At
		1123019 TIR1_ARATH (92-479): 3.54e-59: 206: 19.33		ASK9_ARATH (3-162): 1.41e-69: 208: 47.83
+	Dm
		284995 Q8T437_DROME (56-474): 4.55e-48: 173: 19.16		O77430_DROME (1-163): 3.96e-82: 240: 76.07
+	Dm
		284994 Q8T0K1_DROME (97-478): 2.32e-47: 172: 16.13		O77430_DROME (1-163): 3.96e-82: 240: 76.07
+	Hs
		929111 FBXL2_HUMAN (211-479): 2.98e-39: 148: 22.55		SKP1_HUMAN (1-163): 5.9e-91: 263: 99.39
+	Dm
		1180589 Q8T437_DROME (56-474): 4.55e-48: 173: 19.16		Q7KJ69_DROME (1-163): 1.72e-76: 226: 67.49
+	Dm
		1180588 Q8T0K1_DROME (97-478): 2.32e-47: 172: 16.13		Q7KJ69_DROME (1-163): 1.72e-76: 226: 67.49
+	At
		1338929 BRL1_ARATH (121-473): 5.53e-41: 159: 13.67		ASK4_ARATH (4-162): 1.96e-75: 223: 52.80
+	Dm
		285014 Q9VF10_DROME (202-479): 3.55e-35: 141: 23.59		O77430_DROME (1-163): 3.96e-82: 240: 76.07
+	Dm
		1250282 Q8T437_DROME (56-474): 4.55e-48: 173: 19.16		Q9VWC4_DROME (2-153): 2.29e-65: 198: 56.86
+	Dm
		1180603 Q9VF10_DROME (202-479): 3.55e-35: 141: 23.59		Q7KJ69_DROME (1-163): 1.72e-76: 226: 67.49
+	Dm
		1365165 Q9VF10_DROME (202-479): 3.55e-35: 141: 23.59		Q9VWC4_DROME (2-153): 2.29e-65: 198: 56.86