HitPredict

Interactor 1: RPB3 (P19387)
DNA-directed RNA polymerase II subunit RPB3 (RNA polymerase II subunit 3) (RNA polymerase II subunit B3) (DNA-directed RNA polymerase II 33 kDa polypeptide) (RPB33) (DNA-directed RNA polymerase II subunit C) (RPB31)
Gene: POLR2C

Interactor 2: CPSF6 (Q16630)
Cleavage and polyadenylation specificity factor subunit 6 (Cleavage and polyadenylation specificity factor 68 kDa subunit) (CPSF 68 kDa subunit) (Cleavage factor Im complex 68 kDa subunit) (CFIm68) (Pre-mRNA cleavage factor Im 68 kDa subunit) (Protein HPBRII-4/7)
Gene: CPSF6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 275 Hs			1 551
+	Hs
		583565 RPB3_HUMAN (1-275): 6.89e-138: 391: 100.00		DIDO1_HUMAN (164-416): 4.81e-09: 61.5: 21.59
+	Sc
		376616 RPB3_YEAST (4-271): 9.52e-107: 313: 45.06		PABP_YEAST (82-174): 3.01e-12: 71.1: 27.96