HitPredict

Interactor 1: PROF1 (P07737)
Profilin-1 (Epididymis tissue protein Li 184a) (Profilin I)
Gene: PFN1

Interactor 2: MYO9B (Q13459)
Unconventional myosin-IXb (Unconventional myosin-9b)
Gene: MYO9B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003779 - actin binding GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005938 - cell cortex GO:0016020 - membrane and 1 others more... GO:0031267 - small GTPase binding
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 140 Hs			1 2157
+	Hs
		430397 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO5A_HUMAN (64-1775): 0: 974: 19.82
+	Hs
		430348 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO5C_HUMAN (736-1249): 8.8e-96: 347: 19.74
+	Hs
		70642 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		430075 PROF1_HUMAN (1-140): 1.1e-77: 227: 100.00		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02