HitPredict

Interactor 1: RPAB1 (P19388)
DNA-directed RNA polymerases I, II, and III subunit RPABC1 (RNA polymerases I, II, and III subunit ABC1) (DNA-directed RNA polymerase II 23 kDa polypeptide) (DNA-directed RNA polymerase II subunit E) (RPB5 homolog) (XAP4)
Gene: POLR2E

Interactor 2: RPC8 (Q9Y535)
DNA-directed RNA polymerase III subunit RPC8 (RNA polymerase III subunit C8) (DNA-directed RNA polymerase III subunit H) (RNA polymerase III subunit 22.9 kDa subunit) (RPC22.9)
Gene: POLR3H

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.82	0.60	0.704

Property	Details
Experiments	35271311, 28514442, 24981860, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003677 - DNA binding GO:0003899 - DNA-directed 5'-3' RNA polymerase activity GO:0005654 - nucleoplasm GO:0005666 - RNA polymerase III complex GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 210 Hs			1 204
+	Hs
		583685 RPAB1_HUMAN (1-210): 1.63e-101: 293: 100.00		RPB7_HUMAN (1-199): 5.25e-63: 194: 17.59
+	Sc
		593134 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPC8_YEAST (1-202): 1.09e-72: 220: 42.79
+	Sp
		145818 RPAB1_SCHPO (3-208): 6.38e-83: 246: 43.81		RPB7_SCHPO (2-198): 2.39e-55: 175: 17.59
+	Sc
		593131 RPAB1_YEAST (2-208): 1.31e-77: 233: 43.66		RPB7_YEAST (1-198): 1.19e-54: 173: 18.00