HitPredict

Interactor 1: ERCC3 (P19447)
General transcription and DNA repair factor IIH helicase/translocase subunit XPB (TFIIH subunit XPB) (EC 5.6.2.4) (Basic transcription factor 2 89 kDa subunit) (BTF2 p89) (DNA 3'-5' helicase/translocase XPB) (DNA excision repair protein ERCC-3) (DNA repair protein complementing XP-B cells) (TFIIH basal transcription factor complex 89 kDa subunit) (TFIIH 89 kDa subunit) (TFIIH p89) (Xeroderma pigmentosum group B-complementing protein)
Gene: ERCC3

Interactor 2: LZTS2 (Q9BRK4)
Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)
Gene: LZTS2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.50	0.574

Property	Details
Experiments	28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 782 Hs			1 669
+	Hs
		571365 DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56		SMCA4_HUMAN (18-526): 1.58e-30: 130: 13.06
+	Mm
		1111932 DDX5_MOUSE (198-712): 1.54e-107: 343: 12.87		SMCA4_MOUSE (18-526): 1.74e-30: 130: 12.69
+	Hs
		1145866 DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85		CP135_HUMAN (300-610): 1.6e-09: 63.5: 21.52
+	Hs
		149137 DDX17_HUMAN (225-769): 2.71e-110: 354: 12.85		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		148373 DDX5_HUMAN (198-775): 3.03e-108: 345: 12.56		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		148153 DDX3Y_HUMAN (201-677): 7.95e-102: 329: 10.85		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149273 DDX47_HUMAN (273-769): 5.98e-101: 321: 13.19		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149298 DDX31_HUMAN (204-653): 9.57e-87: 294: 13.92		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36
+	Hs
		149351 DDX18_HUMAN (189-720): 1.43e-85: 287: 14.88		CTRO_HUMAN (327-578): 7.02e-09: 61.3: 16.36