Protein: EGF
Pro-epidermal growth factor (EGF) [Cleaved into: Epidermal growth factor (Urogastrone)]

Gene: EGF
Organism: Homo sapiens
Interactions: 19
UniProt ID: P01133

Gene Ontology (top 5):
GO:0001525 - angiogenesis
GO:0001938 - positive regulation of endothelial cell proliferation
GO:0002092 - positive regulation of receptor internalization
GO:0005085 - guanyl-nucleotide exchange factor activity
GO:0005154 - epidermal growth factor receptor binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

362547

EGFR
Epidermal growth factor receptor

21

20

Small-scale

0.991

High

376577

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

20

Small-scale

0.647

High

376581

ERBB3
Receptor tyrosine-protein kinase erbB-3

1

20

Small-scale

0.647

High

376590

PCOC1
Procollagen C-endopeptidase enhancer 1

1

9

Small-scale

0.647

High

376578

A4
Amyloid-beta precursor protein

2

17

Small-scale

0.595

High

376579

MGST1
Microsomal glutathione S-transferase 1

2

0

High-throughput

0.580

High

376574

EGF
Pro-epidermal growth factor

1

15

Small-scale

0.575

High

376575

LMNA
Prelamin-A/C [Cleaved into: Lamin-A/C

1

1

Small-scale

0.552

High

376583

P85A
Phosphatidylinositol 3-kinase regulatory subunit alpha

1

0

Small-scale

0.537

High

376584

LYOX
Protein-lysine 6-oxidase

1

3

Small-scale

0.536

High

376576

VTNC
Vitronectin

1

3

Small-scale

0.501

High

376582

S10A4
Protein S100-A4

1

1

Small-scale

0.501

High

376585

SHC1
SHC-transforming protein 1

1

14

Small-scale

0.479

High

376589

UBC9
SUMO-conjugating enzyme UBC9

1

0

Small-scale

0.458

High

376580

LMNB1
Lamin-B1

1

1

Small-scale

0.437

High

376586

PCGF2
Polycomb group RING finger protein 2

1

3

Small-scale

0.437

High

376587

SRBP1
Sterol regulatory element-binding protein 1

1

4

Small-scale

0.437

High

376588

EMD
Emerin

1

1

Small-scale

0.437

High


Service provided by Combinatics, Japan

Last updated: 11Aug2025