HitPredict

Interactor 1: RO52 (P19474)
E3 ubiquitin-protein ligase TRIM21 (EC 2.3.2.27) (52 kDa Ro protein) (52 kDa ribonucleoprotein autoantigen Ro/SS-A) (RING finger protein 81) (Ro(SS-A)) (Sjoegren syndrome type A antigen) (SS-A) (Tripartite motif-containing protein 21)
Gene: TRIM21

Interactor 2: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	32051585
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 475 Hs			1 586
+	Hs
		531606 TRI58_HUMAN (1-472): 1.06e-141: 416: 43.52		K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74
+	Hs
		359651 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		360442 TRI39_HUMAN (7-469): 3.45e-150: 440: 38.32		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		821686 TRIM7_HUMAN (11-450): 4.66e-121: 365: 34.03		K2C6C_HUMAN (4-407): 3.4e-87: 283: 22.09
+	Hs
		536792 TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17		LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22
+	Hs
		443320 RO52_HUMAN (1-475): 3.26e-173: 497: 100.00		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		360383 TRIM6_HUMAN (1-466): 1.7e-130: 388: 43.93		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		318774 TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		62675 TRI64_HUMAN (1-449): 3.78e-119: 358: 34.51		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		360110 TRI69_HUMAN (1-466): 3.44e-116: 352: 28.90		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		443583 TRI68_HUMAN (1-465): 4.52e-148: 433: 42.62		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		535315 TRI27_HUMAN (1-466): 2.88e-141: 416: 37.17		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		380469 TRI26_HUMAN (1-354): 6.86e-55: 193: 34.73		K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85
+	Hs
		535455 TRI69_HUMAN (1-466): 3.44e-116: 352: 28.90		GFAP_HUMAN (6-418): 1.55e-27: 117: 29.23
+	Hs
		443767 TRI62_HUMAN (9-467): 3.47e-112: 341: 28.84		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		281054 TRI62_HUMAN (9-467): 3.47e-112: 341: 28.84		KRT38_HUMAN (31-407): 1.45e-25: 111: 28.23
+	Hs
		443785 TRI15_HUMAN (1-453): 6.84e-105: 322: 28.30		VIME_HUMAN (28-390): 5.22e-30: 125: 28.65
+	Hs
		359894 TRI26_HUMAN (1-354): 6.86e-55: 193: 34.73		LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37
+	Hs
		318841 TRIMM_HUMAN (87-468): 1.31e-62: 211: 35.60		K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61
+	Hs
		281022 TRIMM_HUMAN (87-468): 1.31e-62: 211: 35.60		KRT38_HUMAN (31-407): 1.45e-25: 111: 28.23