HitPredict

Interactor 1: TFEB (P19484)
Transcription factor EB (Class E basic helix-loop-helix protein 35) (bHLHe35)
Gene: TFEB

Interactor 2: 1433E (P62258)
14-3-3 protein epsilon (14-3-3E)
Gene: YWHAE

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.81	0.60	0.699

Property	Details
Experiments	28514442, 33961781, 35271311, 36931259
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, cross-linking study
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0019899 - enzyme binding
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 476 Hs			1 255
+	Mm
		910264 TFE3_MOUSE (4-472): 5.71e-66: 223: 44.63		1433E_MOUSE (1-255): 4.87e-154: 430: 100.00
+	Hs
		910039 MLXIP_HUMAN (33-350): 1.28e-35: 142: 14.71		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Sc
		712905 RTG3_YEAST (20-407): 3.17e-43: 161: 14.82		BMH2_YEAST (4-242): 1.14e-134: 382: 77.08
+	Sc
		664789 RTG3_YEAST (20-407): 3.17e-43: 161: 14.82		BMH1_YEAST (2-243): 2.43e-134: 381: 75.72
+	Hs
		297821 K0754_HUMAN (19-459): 5.11e-25: 111: 8.97		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	Hs
		910128 MLX_HUMAN (141-328): 2.8e-25: 107: 15.31		1433E_HUMAN (1-255): 4.87e-154: 430: 100.00
+	At
		285440 PIF3_ARATH (35-300): 6.41e-28: 118: 17.04		14333_ARATH (1-253): 3.45e-147: 413: 74.12
+	At
		285439 PIF3_ARATH (35-300): 6.41e-28: 118: 17.04		14331_ARATH (4-245): 3.88e-144: 405: 75.41