Interactor 1: SL9A1 (P19634)
Sodium/hydrogen exchanger 1 (APNH) (Na(+)/H(+) antiporter, amiloride-sensitive) (Na(+)/H(+) exchanger 1) (NHE-1) (Solute carrier family 9 member 1)
Gene: SLC9A1

Interactor 2: CHP1 (Q99653)
Calcineurin B homologous protein 1 (Calcineurin B-like protein) (Calcium-binding protein CHP) (Calcium-binding protein p22) (EF-hand calcium-binding domain-containing protein p22)
Gene: CHP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.91 1.00 0.958

The method score is based on:

Property Details
Experiments 27751915, 12576672, 8901634, 11350981, 11696366, 31912575
Identification Methods affinity chromatography technology, pull down, far western blotting, two hybrid, fluorescence technology, microscale thermophoresis, isothermal titration calorimetry
Interaction Type physical association, direct interaction

The annotation score is based on:

Property Details
Interacting Pfam domains EF-hand_7~NEXCaM_BD
Common GO terms GO:0005737 - cytoplasm
GO:0005886 - plasma membrane
GO:0005925 - focal adhesion
GO:0015385 - sodium:proton antiporter activity
GO:0045121 - membrane raft
and 4 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 815
Hs

1 195
+ Hs
+ Hs
+ Rn
+ Rn
+ Rn
+ Rn
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Rn
+ Rn
+ Hs
+ Hs
+ Rn
+ Hs
+ Rn
+ Hs
+ Rn

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024