HitPredict

Interactor 1: CSK22 (P19784)
Casein kinase II subunit alpha' (CK II alpha') (EC 2.7.11.1)
Gene: CSNK2A2

Interactor 2: KMT2A (Q03164)
Histone-lysine N-methyltransferase 2A (Lysine N-methyltransferase 2A) (EC 2.1.1.364) (ALL-1) (CXXC-type zinc finger protein 7) (Cysteine methyltransferase KMT2A) (EC 2.1.1.-) (Myeloid/lymphoid or mixed-lineage leukemia) (Myeloid/lymphoid or mixed-lineage leukemia protein 1) (Trithorax-like protein) (Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa) (p320); MLL cleavage product C180 (C-terminal cleavage product of 180 kDa) (p180)]
Gene: KMT2A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.90 0.60 0.738

The method score is based on:

Property Details
Experiments 26186194, 28514442, 27705803, 33961781, 32707033, 23455922
Identification Methods affinity chromatography technology, anti tag coimmunoprecipitation, pull down, tandem affinity purification
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0005634 - nucleus
GO:0005654 - nucleoplasm
GO:0005829 - cytosol
GO:0006915 - apoptotic process
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 350
Hs

1 3969
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024