HitPredict

Interactor 1: HSP60 (P19882)
Heat shock protein 60, mitochondrial (CPN60) (P66) (Stimulator factor I 66 kDa component)
Gene: HSP60

Interactor 2: PP2A1 (P23594)
Serine/threonine-protein phosphatase PP2A-1 catalytic subunit (EC 3.1.3.16)
Gene: PPH21

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	11805837, 19536198
Identification Methods	anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 572 Sc			1 369
+	Sc
		587941 HSP60_YEAST (1-548): 0: 542: 100.00		PP2A2_YEAST (1-369): 0: 561: 87.80
+	Hs
		915267 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		PP2AB_HUMAN (62-369): 0: 534: 73.70
+	Hs
		930969 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		PP2AA_HUMAN (62-369): 0: 532: 74.03
+	Hs
		499667 CH60_HUMAN (4-556): 5.37e-180: 521: 54.38		PP1A_HUMAN (57-356): 0: 524: 45.52
+	Hs
		890997 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		PP4C_HUMAN (67-369): 0: 524: 59.87
+	Hs
		821154 TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84		PP2AB_HUMAN (62-369): 0: 534: 73.70
+	Hs
		826603 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		PP2AB_HUMAN (62-369): 0: 534: 73.70
+	Hs
		821161 TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84		PP2AA_HUMAN (62-369): 0: 532: 74.03
+	Hs
		826610 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		PP2AA_HUMAN (62-369): 0: 532: 74.03
+	Hs
		821143 TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84		PP4C_HUMAN (67-369): 0: 524: 59.87
+	Hs
		826591 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		PP4C_HUMAN (67-369): 0: 524: 59.87
+	Sc
		587923 HSP60_YEAST (1-548): 0: 542: 100.00		PP11_YEAST (71-369): 1.43e-131: 380: 55.08
+	Hs
		135491 TCPH_HUMAN (11-559): 1.16e-177: 514: 18.04		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89
+	Hs
		135397 TCPE_HUMAN (1-553): 2.71e-172: 500: 16.84		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89
+	Hs
		135401 TCPG_HUMAN (10-568): 3.04e-172: 500: 14.46		PPP6_HUMAN (70-366): 3.1e-129: 374: 55.89