HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF13 (Q15543)
Transcription initiation factor TFIID subunit 13 (Transcription initiation factor TFIID 18 kDa subunit) (TAF(II)18) (TAFII-18) (TAFII18)
Gene: TAF13

Species: Homo sapiens

Source: dip

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.76	1.00	0.877

The method score is based on:

Property	Details
Experiments	29111974, 19240132, 7729427
Identification Methods	pull down, two hybrid, molecular sieving, coimmunoprecipitation
Interaction Type	direct interaction, physical association

The annotation score is based on:

Property	Details
Interacting Pfam domains	TBP~TFIID-18kDa
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0006352 - DNA-templated transcription initiation GO:0006366 - transcription by RNA polymerase II and 5 others more... GO:0006367 - transcription initiation at RNA polymerase II promoter GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0042789 - mRNA transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1	339
Hs

1	124

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024