HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: TAF4B (Q92750)
Transcription initiation factor TFIID subunit 4B (Transcription initiation factor TFIID 105 kDa subunit) (TAF(II)105) (TAFII-105) (TAFII105)
Gene: TAF4B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.62	1.00	0.789

The method score is based on:

Property	Details
Experiments	35271311, 8858156
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

The annotation score is based on:

Property	Details
Interacting Pfam domains	TAF4~TBP
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005669 - transcription factor TFIID complex GO:0005737 - cytoplasm GO:0006367 - transcription initiation at RNA polymerase II promoter and 5 others more... GO:0007283 - spermatogenesis GO:0016251 - RNA polymerase II general transcription initiation factor activity GO:0042789 - mRNA transcription by RNA polymerase II GO:0051123 - RNA polymerase II preinitiation complex assembly GO:0060261 - positive regulation of transcription initiation by RNA polymerase II
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1	339
Hs

1	862

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024