Protein: CHM2B
Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2)

Gene: CHM2B, CHMP2B
Organism: Homo sapiens
Interactions: 78
UniProt ID: Q9UQN3

Gene Ontology (top 5):
GO:0000421 - autophagosome membrane
GO:0000776 - kinetochore
GO:0000815 - ESCRT III complex
GO:0001778 - plasma membrane repair
GO:0005643 - nuclear pore

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1462769

CHMP3
Charged multivesicular body protein 3

3

18

Small-scale

0.844

High

1433130

CHM4B
Charged multivesicular body protein 4b

2

18

Small-scale

0.799

High

1446003

VTA1
Vacuolar protein sorting-associated protein VTA1 homolog

1

11

High-throughput

0.665

High

1462767

CHM2B
Charged multivesicular body protein 2b

1

18

High-throughput

0.656

High

276933

VPS4B
Vacuolar protein sorting-associated protein 4B

2

20

Small-scale

0.611

High

51127

PKHG3
Pleckstrin homology domain-containing family G member 3

2

2

High-throughput

0.571

High

1452485

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.549

High

564574

CFTR
Cystic fibrosis transmembrane conductance regulator

1

3

High-throughput

0.541

High

1090981

TRAF2
TNF receptor-associated factor 2

1

4

High-throughput

0.541

High

292780

RENR
Renin receptor

1

1

High-throughput

0.536

High

483264

CLCA
Clathrin light chain A

1

8

High-throughput

0.536

High

901108

RAB5C
Ras-related protein Rab-5C

1

9

High-throughput

0.536

High

901686

RAB7A
Ras-related protein Rab-7a

1

12

High-throughput

0.536

High

1277806

MYH14
Myosin-14

1

6

High-throughput

0.536

High

1400195

SYGP1
Ras/Rap GTPase-activating protein SynGAP

1

6

High-throughput

0.536

High

1462768

GOT1B
Vesicle transport protein GOT1B

1

2

High-throughput

0.536

High

317950

LTN1
E3 ubiquitin-protein ligase listerin

1

0

High-throughput

0.513

High

1099827

MD2L1
Mitotic spindle assembly checkpoint protein MAD2A

1

0

High-throughput

0.513

High

1204405

SGO1
Shugoshin 1

1

0

High-throughput

0.513

High

1290397

IFTAP
Intraflagellar transport-associated protein

1

0

High-throughput

0.513

High

209699

SERA
D-3-phosphoglycerate dehydrogenase

1

2

High-throughput

0.508

High

828262

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

11

Small-scale

0.501

High

1462136

VPS4A
Vacuolar protein sorting-associated protein 4A

1

20

Small-scale

0.501

High

1462770

FBX7
F-box only protein 7

1

1

High-throughput

0.501

High

822911

VHL
von Hippel-Lindau disease tumor suppressor

1

0

High-throughput

0.493

High

1461755

CAPS1
Calcium-dependent secretion activator 1

1

0

High-throughput

0.493

High

1329015

ZBTB2
Zinc finger and BTB domain-containing protein 2

1

5

High-throughput

0.489

High

1336504

PNMA1
Paraneoplastic antigen Ma1

1

0

High-throughput

0.486

High

1389035

MASU1
Mitochondrial assembly of ribosomal large subunit protein 1

1

0

High-throughput

0.486

High

791848

SYUA
Alpha-synuclein

1

4

High-throughput

0.481

High

169284

CASQ2
Calsequestrin-2

1

4

High-throughput

0.479

High

173570

XPO1
Exportin-1

1

9

High-throughput

0.479

High

189933

STX7
Syntaxin-7

1

1

High-throughput

0.479

High

243312

PRKN
E3 ubiquitin-protein ligase parkin

1

2

High-throughput

0.479

High

346515

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

9

High-throughput

0.479

High

364046

EGFR
Epidermal growth factor receptor

1

11

High-throughput

0.479

High

439882

INSR
Insulin receptor

1

4

High-throughput

0.479

High

464083

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

1

7

High-throughput

0.479

High

556430

CADH1
Cadherin-1

1

3

High-throughput

0.479

High

560559

IFM1
Interferon-induced transmembrane protein 1

1

2

High-throughput

0.479

High

583118

VATB1
V-type proton ATPase subunit B, kidney isoform

1

8

High-throughput

0.479

High

613227

EGR1
Early growth response protein 1

1

1

High-throughput

0.479

High

630094

BTF3
Transcription factor BTF3

1

6

High-throughput

0.479

High

648745

FGFR4
Fibroblast growth factor receptor 4

1

3

High-throughput

0.479

High

652601

NR4A1
Nuclear receptor subfamily 4immunitygroup A member 1

1

3

High-throughput

0.479

High

788269

ODO2
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

3

High-throughput

0.479

High

862562

YAP1
Transcriptional coactivator YAP1

1

1

Small-scale

0.479

High

895160

EMD
Emerin

1

1

High-throughput

0.479

High

937974

FOXA1
Hepatocyte nuclear factor 3-alpha

1

3

High-throughput

0.479

High

953190

ACTB
Actin, cytoplasmic 1

1

4

High-throughput

0.479

High

1031602

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.479

High

1108295

SQSTM
Sequestosome-1

1

7

Small-scale

0.479

High

1125733

FKBP8
Peptidyl-prolyl cis-trans isomerase FKBP8

1

3

High-throughput

0.479

High

1289729

NAA40
N-alpha-acetyltransferase 40

1

1

High-throughput

0.479

High

1330982

CGAS
Cyclic GMP-AMP synthase

1

6

High-throughput

0.479

High

1364705

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

2

High-throughput

0.479

High

1370473

CSN5
COP9 signalosome complex subunit 5

1

1

High-throughput

0.479

High

1400352

FMNL2
Formin-like protein 2

1

1

High-throughput

0.479

High

1434254

PKHA4
Pleckstrin homology domain-containing family A member 4

1

10

High-throughput

0.479

High

1446846

TRI36
E3 ubiquitin-protein ligase TRIM36

1

7

High-throughput

0.479

High

1459340

ZRAN1
Ubiquitin thioesterase ZRANB1

1

7

High-throughput

0.479

High

540759

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

1449992

T106B
Transmembrane protein 106B

1

0

Small-scale

0.458

High

1258213

UBP54
Ubiquitin carboxyl-terminal hydrolase 54

1

8

Small-scale

0.457

High

883964

CENPF
Centromere protein F

1

14

High-throughput

0.457

High

766021

BMI1
Polycomb complex protein BMI-1

1

9

High-throughput

0.445

High

800596

VATA
V-type proton ATPase catalytic subunit A

1

14

High-throughput

0.445

High

1096864

RFA4
Replication protein A 30 kDa subunit

1

3

High-throughput

0.437

High

1367612

ESR2
Estrogen receptor beta

1

3

High-throughput

0.437

High

1459631

SEC63
Translocation protein SEC63 homolog

1

6

High-throughput

0.437

High

1461705

HECD1
E3 ubiquitin-protein ligase HECTD1

1

2

High-throughput

0.437

High

784766

ATPG
ATP synthase F(1) complex subunit gamma, mitochondrial

1

0

High-throughput

0.282

High

1434606

SUV92
Histone-lysine N-methyltransferase SUV39H2

1

0

High-throughput

0.279

Low

940706

ATP5I
ATP synthase F(0) complex subunit e, mitochondrial

1

0

High-throughput

0.269

Low

1404283

SEC62
Translocation protein SEC62

1

0

High-throughput

0.249

Low

1450977

KBTB4
Kelch repeat and BTB domain-containing protein 4

1

0

High-throughput

0.249

Low

1420484

DPY30
Protein dpy-30 homolog

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025