HitPredict

Interactor 1: TBP (P20226)
TATA-box-binding protein (TATA sequence-binding protein) (TATA-binding factor) (TATA-box factor) (Transcription initiation factor TFIID TBP subunit)
Gene: TBP

Interactor 2: FOXP1 (Q9H334)
Forkhead box protein P1 (Mac-1-regulated forkhead) (MFH)
Gene: FOXP1

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	25609649
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000785 - chromatin GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001046 - core promoter sequence-specific DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 339 Hs			1 677
+	Hs
		175953 TBP_HUMAN (1-339): 7.86e-144: 411: 100.00		FOXN1_HUMAN (204-668): 1.99e-92: 301: 18.68
+	Mm
		661514 TBP_MOUSE (1-339): 8.88e-142: 405: 91.15		FOXP3_MOUSE (172-551): 2.02e-84: 274: 35.51
+	Hs
		589833 TBP_HUMAN (1-339): 7.86e-144: 411: 100.00		FOXK2_HUMAN (364-657): 1.47e-50: 188: 19.81
+	Hs
		589903 TBP_HUMAN (1-339): 7.86e-144: 411: 100.00		FOXJ1_HUMAN (403-662): 5.94e-52: 187: 24.73
+	Hs
		589930 TBP_HUMAN (1-339): 7.86e-144: 411: 100.00		FOXJ2_HUMAN (465-546): 8.98e-13: 73.2: 42.22