HitPredict

Interactor 1: PO5F1 (P20263)
POU domain, class 5, transcription factor 1 (NF-A3) (Octamer-binding protein 3) (Oct-3) (Octamer-binding protein 4) (Oct-4) (Octamer-binding transcription factor 3) (OTF-3)
Gene: Pou5f1

Interactor 2: SOX2 (P48432)
Transcription factor SOX-2
Gene: SOX2

Species: Mus musculus

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.89 1.00 0.947

The method score is based on:

Property Details
Experiments 20362541, 15863505, 22344693, 31077711, 17507372, 23108051
Identification Methods affinity chromatography technology, pull down, anti tag coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains HMG_box~Pou
Common GO terms GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0000976 - transcription cis-regulatory region binding
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
and 24 others

more...
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 352
Mm

1 319
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+ Ce
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024