Interactor 1: CD22 (P20273)
B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
Gene: CD22

Interactor 2: CD22 (P20273)
B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
Gene: CD22

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 16408005
Identification Methods anti tag coimmunoprecipitation
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~Ig_2, C2-set_2~Ig_3, Ig_2~Ig_2, Ig_2~Ig_3, Ig_3~Ig_3
Common GO terms GO:0001791 - IgM binding
GO:0002638 - negative regulation of immunoglobulin production
GO:0005102 - signaling receptor binding
GO:0005737 - cytoplasm
GO:0005769 - early endosome
and 18 others

more...

Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 847
Hs

1 847
+ Hs
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+ Mm
+ Dm
+ Dm
+ Dr
+ Mm
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+ Hs
+ Hs
+ Mm
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+ Dm
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+ Dm

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Last updated: 15 Jul 2024