Interactor 1: CD22 (P20273)
B-cell receptor CD22 (B-lymphocyte cell adhesion molecule) (BL-CAM) (Sialic acid-binding Ig-like lectin 2) (Siglec-2) (T-cell surface antigen Leu-14) (CD antigen CD22)
Gene: CD22

Interactor 2: MUC18 (P43121)
Cell surface glycoprotein MUC18 (Cell surface glycoprotein P1H12) (Melanoma cell adhesion molecule) (Melanoma-associated antigen A32) (Melanoma-associated antigen MUC18) (S-endo 1 endothelial-associated antigen) (CD antigen CD146)
Gene: MCAM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score Annotation score Interaction score
0.38 1.00 0.618

The method score is based on:

Property Details
Experiments 38117590
Identification Methods proximity labelling technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains C2-set_2~C2-set_2, C2-set_2~Ig_3, C2-set_2~V-set, C2-set_2~Ig_2, Ig_2~Ig_3, Ig_2~V-set, Ig_3~Ig_3, Ig_3~V-set
Common GO terms GO:0005886 - plasma membrane
GO:0007155 - cell adhesion
GO:0009897 - external side of plasma membrane
Homologous interactions 17

Homologous interactions

Color coding for hit scores

1 847
Hs

1 646
+ Hs
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+ Mm
+ Dm
+ Dm
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+ Dr
+ Mm
+ Mm
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+ Dm

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024