Protein: MET30
F-box protein MET30 (E3 ubiquitin ligase complex SCF(Met30) subunit MET30) (Methionine-requiring protein 30)

Gene: MET30
Organism: Saccharomyces cerevisiae S288C
Interactions: 126
UniProt ID: P39014

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000209 - protein polyubiquitination
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006357 - regulation of transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

809273

SKP1
Suppressor of kinetochore protein 1

21

20

Small-scale

0.989

High

809301

CDC53
Cell division control protein 53

10

20

Small-scale

0.978

High

574797

UBC3
Ubiquitin-conjugating enzyme E2-34 kDa

3

20

Small-scale

0.839

High

509552

UBI4P
Polyubiquitin [Cleaved into: Ubiquitin]

3

9

Small-scale

0.834

High

736382

MET4
Transcriptional activator of sulfur metabolism MET4

11

0

Small-scale

0.726

High

809251

MET30
F-box protein MET30

1

17

Small-scale

0.715

High

809285

RUB1
NEDD8-like protein RUB1

1

8

High-throughput

0.691

High

679683

CDC48
Cell division control protein 48

4

11

Small-scale

0.680

High

809297

RBX1
RING-box protein HRT1

3

13

Small-scale

0.650

High

809286

METX
Putative cystathionine gamma-synthase YML082W

3

2

Small-scale

0.648

High

470750

GPA1
Guanine nucleotide-binding protein alpha-1 subunit

1

3

Small-scale

0.621

High

460728

CDC4
Cell division control protein 4

1

19

Small-scale

0.618

High

779229

CENPA
Histone H3-like centromeric protein CSE4

1

8

Small-scale

0.618

High

809283

MET31
Transcriptional regulator MET31

2

5

Small-scale

0.614

High

809271

MET7
Cystathionine gamma-synthase

2

2

Small-scale

0.595

High

598402

TUP1
General transcriptional corepressor TUP1

1

19

High-throughput

0.590

High

666460

DBP2
ATP-dependent RNA helicase DBP2

1

11

High-throughput

0.590

High

809275

INO80
Chromatin-remodeling ATPase INO80

1

15

High-throughput

0.590

High

809281

UBC7
Ubiquitin-conjugating enzyme E2 7

1

20

High-throughput

0.590

High

809270

BIT61
Target of rapamycin complex 2 subunit BIT61

2

1

High-throughput

0.590

High

647111

RPC2
DNA-directed RNA polymerase III subunit RPC2

2

2

High-throughput

0.565

High

797272

YBY8
Uncharacterized protein YBR138C

2

0

High-throughput

0.565

High

809256

EDC3
Enhancer of mRNA-decapping protein 3

2

0

High-throughput

0.565

High

809302

SRL2
Protein SRL2

2

0

High-throughput

0.565

High

794705

SEA4
SEH-associated protein 4

1

0

High-throughput

0.560

High

809258

SSB2
Ribosome-associated molecular chaperone SSB2

2

16

High-throughput

0.552

High

798527

BIT2
Probable target of rapamycin complex 2 subunit BIT2

2

1

High-throughput

0.539

High

670711

SIS1
Protein SIS1

1

15

High-throughput

0.536

High

779056

EF1G2
Elongation factor 1-gamma 2

1

4

High-throughput

0.536

High

633161

MAK11
Protein MAK11

1

18

High-throughput

0.528

High

809299

SGT1
Protein SGT1

2

5

Small-scale

0.526

High

748844

SWE1
Mitosis inhibitor protein kinase SWE1

1

14

Small-scale

0.515

High

386710

TBB
Tubulin beta chain

1

13

High-throughput

0.500

High

392735

HSP82
ATP-dependent molecular chaperone HSP82

1

14

High-throughput

0.500

High

394564

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.500

High

416434

HXKA
Hexokinase-1

1

2

High-throughput

0.500

High

531328

METK1
S-adenosylmethionine synthase 1

1

2

High-throughput

0.500

High

592256

VATB
V-type proton ATPase subunit B

1

9

High-throughput

0.500

High

676003

MAS5
Mitochondrial protein import protein MAS5

1

13

High-throughput

0.500

High

809269

ERG10
Acetyl-CoA acetyltransferase

1

5

Small-scale

0.481

High

590627

HSP26
Heat shock protein 26

1

0

High-throughput

0.479

High

470718

MET3
Sulfate adenylyltransferase

1

2

High-throughput

0.479

High

657090

IF5A1
Eukaryotic translation initiation factor 5A-1

1

2

High-throughput

0.479

High

707108

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

757874

UBX1
UBX domain-containing protein 1

1

2

Small-scale

0.479

High

776572

DEF1
RNA polymerase II degradation factor 1

1

6

High-throughput

0.479

High

809257

LSM4
LSM complex subunit LSM4

1

4

High-throughput

0.479

High

809268

GTS1
Protein GTS1

1

2

High-throughput

0.479

High

809282

KAPS
Adenylyl-sulfate kinase

1

2

High-throughput

0.479

High

809293

WHI4
Protein WHI4

1

2

High-throughput

0.479

High

809303

MET32
Transcriptional regulator MET32

1

4

Small-scale

0.479

High

616422

SEC18
Vesicular-fusion protein SEC18

1

10

High-throughput

0.464

High

809265

MET28
Transcriptional activator of sulfur metabolism MET28

1

0

Small-scale

0.460

High

432325

METE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase

1

0

High-throughput

0.458

High

488369

HO
Homothallic switching endonuclease

1

0

Small-scale

0.458

High

809253

MET10
Sulfite reductase [NADPH] flavoprotein component

1

0

High-throughput

0.458

High

809272

MET5
Sulfite reductase [NADPH] subunit beta

1

0

High-throughput

0.458

High

460971

LTE1
Guanine nucleotide exchange factor LTE1

1

4

High-throughput

0.457

High

597610

CDC23
Anaphase-promoting complex subunit CDC23

1

10

High-throughput

0.457

High

614824

SNF5
SWI/SNF chromatin-remodeling complex subunit SNF5

1

9

High-throughput

0.457

High

646039

KIN3
Serine/threonine-protein kinase KIN3

1

13

High-throughput

0.457

High

735783

TFC1
Transcription factor tau 95 kDa subunit

1

2

High-throughput

0.457

High

739072

PAN1
Actin cytoskeleton-regulatory complex protein PAN1

1

7

High-throughput

0.457

High

745419

FZF1
Zinc finger protein FZF1

1

10

High-throughput

0.457

High

753080

NIP80
Protein NIP100

1

15

High-throughput

0.457

High

763226

PP2C1
Protein phosphatase 2C homolog 1

1

1

High-throughput

0.457

High

778330

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.457

High

778881

PTK1
Serine/threonine-protein kinase PTK1/STK1

1

6

High-throughput

0.457

High

805343

UBA4
Adenylyltransferase and sulfurtransferase UBA4

1

3

High-throughput

0.457

High

809252

YJU6
Putative transcriptional regulatory protein YJL206C

1

1

High-throughput

0.457

High

809288

CYK2
Cytokinesis protein 2

1

2

High-throughput

0.457

High

555076

G6PI
Glucose-6-phosphate isomerase

1

1

High-throughput

0.457

High

510492

HSP77
Import motor subunit, mitochondrial

1

17

High-throughput

0.445

High

523964

HSP71
Heat shock protein SSA1

1

14

High-throughput

0.445

High

544890

SSB1
Ribosome-associated molecular chaperone SSB1

1

16

High-throughput

0.445

High

809278

PFD4
Prefoldin subunit 4

1

6

High-throughput

0.445

High

366021

INV2
Invertase 2

1

0

High-throughput

0.438

High

423589

ARGR2
Arginine metabolism regulation protein II

1

0

High-throughput

0.438

High

677283

PEX34
Peroxisomal membrane protein PEX34

1

0

High-throughput

0.438

High

735381

MCM10
Minichromosome maintenance protein 10

1

0

High-throughput

0.438

High

745473

SLX5
E3 ubiquitin-protein ligase complex SLX5-SLX8 subunit SLX5

1

0

High-throughput

0.438

High

806068

PEX18
Peroxisomal membrane protein PEX18

1

0

High-throughput

0.438

High

809255

OAF1
Oleate-activated transcription factor 1

1

0

High-throughput

0.438

High

809263

DPH1
2-(3-amino-3-carboxypropyl)histidine synthase subunit 1

1

0

High-throughput

0.438

High

809264

SDS3
Transcriptional regulatory protein SDS3

1

0

High-throughput

0.438

High

809279

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.438

High

809291

VPS74
Vacuolar protein sorting-associated protein 74

1

0

High-throughput

0.438

High

809295

LMO1
ELMO family protein LMO1

1

0

High-throughput

0.438

High

582464

SEC23
Protein transport protein SEC23

1

3

High-throughput

0.437

High

619164

IF5A2
Eukaryotic translation initiation factor 5A-2

1

2

High-throughput

0.437

High

809262

SEC24
Protein transport protein SEC24

1

3

High-throughput

0.437

High

809274

ALAT1
Alanine aminotransferase, mitochondrial

1

3

High-throughput

0.437

High

561311

DPOLA
DNA polymerase alpha catalytic subunit A

1

2

High-throughput

0.417

High

809254

FLO9
Flocculation protein FLO9

1

17

High-throughput

0.417

High

809261

BNR1
BNI1-related protein 1

1

2

High-throughput

0.417

High

809276

PXR1
Protein PXR1

1

1

High-throughput

0.417

High

809289

ENT2
Epsin-2

1

1

High-throughput

0.417

High

809290

PIG1
Serine/threonine-protein phosphatase 1 regulatory subunit PIG1

1

1

High-throughput

0.417

High

809305

RDL1
Thiosulfate:glutathione sulfurtransferase

1

1

High-throughput

0.417

High

747680

MNS1
Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase

2

0

High-throughput

0.307

High

809277

CWC25
Pre-mRNA-splicing factor CWC25

2

0

High-throughput

0.295

High

809284

YD095
Putative uncharacterized protein YDR095C

2

0

High-throughput

0.295

High

809306

YVC1
Calcium channel YVC1

2

0

High-throughput

0.295

High

368668

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

809260

MPM1
Mitochondrial peculiar membrane protein 1

1

0

High-throughput

0.261

Low

809304

ATG9
Autophagy-related protein 9

1

0

Small-scale

0.251

Low

677139

LRE1
Laminarase-resistance protein LRE1

1

0

High-throughput

0.249

Low

677804

ILV6
Acetolactate synthase small subunit, mitochondrial

1

0

High-throughput

0.249

Low

781986

UTH1
Probable secreted beta-glucosidase UTH1

1

0

High-throughput

0.249

Low

150217

YL269
Putative uncharacterized protein YLR269C

1

0

High-throughput

0.238

Low

754460

SPO23
Sporulation protein 23

1

0

High-throughput

0.238

Low

793264

TAT1
Valine/tyrosine/tryptophan amino-acid permease 1

1

0

High-throughput

0.238

Low

794313

YB9Z
Inactive deaminase YBR284W

1

0

High-throughput

0.238

Low

797952

ATG12
Ubiquitin-like protein ATG12

1

0

High-throughput

0.238

Low

800444

ERG7
Lanosterol synthase ERG7

1

0

High-throughput

0.238

Low

809259

NTA1
Protein N-terminal amidase

1

0

High-throughput

0.238

Low

809266

YIW4
Putative uncharacterized protein YIR044C

1

0

High-throughput

0.238

Low

809267

YJV8
Putative acetyltransferase YJL218W

1

0

High-throughput

0.238

Low

809280

APP1
Phosphatidate phosphatase APP1

1

0

High-throughput

0.238

Low

809287

YDR14
Uncharacterized protein YDR114C

1

0

High-throughput

0.238

Low

809292

YD094
Putative uncharacterized protein YDL094C

1

0

High-throughput

0.238

Low

809294

YD241
Uncharacterized protein YDL241W

1

0

High-throughput

0.238

Low

809296

YO036
Uncharacterized protein YOL036W

1

0

High-throughput

0.238

Low

809298

BSC6
Bypass of stop codon protein 6

1

0

High-throughput

0.238

Low

809300

FEX1
Fluoride export protein 1

1

0

High-throughput

0.238

Low


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Last updated: 11Aug2025