Interactor 1: TNR1B (P20333)
Tumor necrosis factor receptor superfamily member 1B (Tumor necrosis factor receptor 2) (TNF-R2) (Tumor necrosis factor receptor type II) (TNF-RII) (TNFR-II) (p75) (p80 TNF-alpha receptor) (CD antigen CD120b) (Etanercept) [Cleaved into: Tumor necrosis factor receptor superfamily member 1b, membrane form; Tumor necrosis factor-binding protein 2 (TBP-2) (TBPII)]
Gene: TNFRSF1B

Interactor 2: TRADD (Q15628)
Tumor necrosis factor receptor type 1-associated DEATH domain protein (TNFR1-associated DEATH domain protein) (TNFRSF1A-associated via death domain)
Gene: TRADD

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.56 0.60 0.584

The method score is based on:

Property Details
Experiments 36185580, 19287455
Identification Methods affinity chromatography technology
Interaction Type physical association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0002947 - tumor necrosis factor receptor superfamily complex
GO:0005886 - plasma membrane
GO:0033209 - tumor necrosis factor-mediated signaling pathway
GO:0097191 - extrinsic apoptotic signaling pathway
Homologous interactions 9

Homologous interactions

Color coding for hit scores

1 461
Hs

1 312
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+ Rn
+ Mm
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024