HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: DEN4C (Q5VZ89)
DENN domain-containing protein 4C
Gene: DENND4C

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~dDENN, DENN~Ras, Ras~uDENN
Common GO terms	GO:0005886 - plasma membrane GO:0015031 - protein transport GO:0030659 - cytoplasmic vesicle membrane GO:0032593 - insulin-responsive compartment
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 218 Hs			1 1909
+	Hs
		895124 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		DEN4C_HUMAN (1-1909): 0: 2541: 100.00
+	Hs
		914128 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		DEN4C_HUMAN (1-1909): 0: 2541: 100.00
+	Hs
		591906 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		MYCPP_HUMAN (1-1909): 0: 2109: 47.94
+	Hs
		914171 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		MYCPP_HUMAN (1-1909): 0: 2109: 47.94
+	Dm
		185684 O18335_DROME (5-185): 7.23e-54: 173: 50.55		Q7KSP6_DROME (188-1302): 0: 1083: 17.36
+	Hs
		914156 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		DEN5B_HUMAN (201-755): 1.33e-151: 504: 22.04
+	Hs
		895162 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		DEN6A_HUMAN (173-660): 4.78e-82: 285: 13.67
+	Hs
		1079940 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		DEN6A_HUMAN (173-660): 4.78e-82: 285: 13.67
+	Hs
		914194 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		DEN6A_HUMAN (173-660): 4.78e-82: 285: 13.67
+	Dm
		185721 O18335_DROME (5-185): 7.23e-54: 173: 50.55		CRAG_DROME (1683-1909): 2.32e-85: 312: 37.45