HitPredict

Interactor 1: RAB4A (P20338)
Ras-related protein Rab-4A (EC 3.6.5.2)
Gene: RAB4A

Interactor 2: RBGP1 (Q9Y3P9)
Rab GTPase-activating protein 1 (GAP and centrosome-associated protein) (Rab6 GTPase-activating protein GAPCenA)
Gene: RABGAP1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.80	0.741

Property	Details
Experiments	34079125, 37232246, 21988832
Identification Methods	proximity labelling technology, two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 218 Hs			1 1069
+	Hs
		914482 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		RBGP1_HUMAN (1-1069): 0: 1042: 100.00
+	Hs
		234370 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		EVI5_HUMAN (484-1067): 7.35e-89: 305: 25.60
+	Hs
		234378 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		EVI5_HUMAN (484-1067): 7.35e-89: 305: 25.60
+	Hs
		895137 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		TBCD9_HUMAN (367-877): 8.18e-78: 281: 18.18
+	Hs
		1079952 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		EVI5L_HUMAN (475-1066): 3.65e-85: 294: 25.37
+	Hs
		914275 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		EVI5L_HUMAN (475-1066): 3.65e-85: 294: 25.37
+	Hs
		895106 RAB2A_HUMAN (10-197): 2.28e-93: 273: 56.92		TB10B_HUMAN (426-846): 7.33e-75: 266: 21.07
+	Dm
		1197047 Q86BK8_DROME (3-218): 6.99e-93: 273: 56.94		EVI5_DROME (494-1067): 1.65e-73: 262: 29.21
+	Os
		1130873 Q6YY17_ORYSJ (9-197): 1.31e-91: 268: 55.03		Q5SMT0_ORYSJ (383-806): 4.24e-74: 260: 16.96
+	Hs
		321271 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		TBCD8_HUMAN (368-887): 5.07e-74: 268: 19.33
+	Hs
		81691 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		RBG10_HUMAN (839-1064): 2.27e-78: 258: 67.70
+	Hs
		321281 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		TBCD8_HUMAN (368-887): 5.07e-74: 268: 19.33
+	Hs
		1079972 RB11B_HUMAN (3-217): 1.16e-83: 249: 43.26		TBC14_HUMAN (443-840): 2.26e-76: 267: 23.13
+	Hs
		914176 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		TBCD1_HUMAN (382-918): 1.34e-73: 267: 24.22
+	Hs
		914423 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		TBC14_HUMAN (443-840): 2.26e-76: 267: 23.13
+	Hs
		232698 RAB2B_HUMAN (10-218): 1.65e-82: 246: 51.87		TBCD4_HUMAN (431-905): 6.39e-74: 269: 26.12
+	Hs
		81703 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		RBG10_HUMAN (839-1064): 2.27e-78: 258: 67.70
+	Os
		772871 RIC2_ORYSJ (1-217): 1.78e-82: 246: 38.99		Q5SMT0_ORYSJ (383-806): 4.24e-74: 260: 16.96
+	Hs
		233033 RAB4A_HUMAN (1-218): 5.41e-88: 260: 100.00		TBC12_HUMAN (543-795): 5.56e-23: 107: 28.26
+	Hs
		233036 RB11A_HUMAN (3-217): 8.33e-84: 249: 42.33		TBC12_HUMAN (543-795): 5.56e-23: 107: 28.26