HitPredict

Interactor 1: RAB5A (P20339)
Ras-related protein Rab-5A (EC 3.6.5.2)
Gene: RAB5A

Interactor 2: VAMP2 (P63027)
Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2)
Gene: VAMP2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0008021 - synaptic vesicle GO:0030669 - clathrin-coated endocytic vesicle membrane GO:0043231 - intracellular membrane-bounded organelle
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 215 Hs			1 116
+	Hs
		592170 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		844447 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		261637 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		850554 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		VAMP7_HUMAN (3-96): 2.69e-30: 109: 31.31
+	Hs
		263168 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180813 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		592276 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		592467 RAB5A_HUMAN (1-215): 2.09e-88: 260: 100.00		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		261643 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		1079428 RAB1B_HUMAN (13-213): 3.05e-87: 257: 41.79		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		918878 RAB1A_HUMAN (11-213): 2.59e-87: 257: 41.18		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		844474 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		VAMP2_HUMAN (25-116): 9.9e-26: 94.7: 100.00
+	Hs
		263198 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		261649 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		VAMP4_HUMAN (18-99): 1.04e-26: 97.8: 35.37
+	Hs
		180835 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		844540 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		VAMP3_HUMAN (26-98): 7.88e-25: 92: 91.78
+	Hs
		844710 RAB5C_HUMAN (1-215): 3.96e-85: 252: 86.57		VAMP8_HUMAN (20-99): 2.06e-24: 90.9: 32.50
+	Hs
		263215 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		SC22B_HUMAN (1-115): 4.12e-24: 93.2: 17.09
+	Hs
		180855 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		YKT6_HUMAN (5-85): 5.79e-24: 92.4: 24.69
+	Hs
		87580 RB11A_HUMAN (11-215): 7.77e-83: 247: 38.32		C9JXZ5_HUMAN (46-99): 8.01e-21: 80.9: 37.04