Interactor 1: SRP54 (P20424)
Signal recognition particle subunit SRP54 (EC 3.6.5.4) (Signal recognition particle 54 kDa protein homolog)
Gene: SRP54

Interactor 2: SEC65 (P29478)
Signal recognition particle subunit SEC65
Gene: SEC65

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.918

The method score is based on:

Property Details
Experiments 11805826, 10921896, 7925282, 16429126, 37968396
Identification Methods tandem affinity purification, biochemical, affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains SRP19~SRP_SPB
Common GO terms GO:0005786 - signal recognition particle, endoplasmic reticulum targeting
GO:0006614 - SRP-dependent cotranslational protein targeting to membrane
GO:0006617 - SRP-dependent cotranslational protein targeting to membrane, signal sequence recognition
GO:0008312 - 7S RNA binding
Homologous interactions 3

Homologous interactions

Color coding for hit scores

1 541
Sc

1 273
+ Hs
+ Mj
+ Hs

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Last updated: 15 Jul 2024