Protein: RDH12
Retinol dehydrogenase 12 (EC 1.1.1.300) (All-trans and 9-cis retinol dehydrogenase) (Short chain dehydrogenase/reductase family 7C member 2)

Gene: RDH12
Organism: Homo sapiens
Interactions: 48
UniProt ID: Q96NR8

Gene Ontology (top 5):
GO:0001523 - retinoid metabolic process
GO:0001917 - photoreceptor inner segment
GO:0004745 - all-trans-retinol dehydrogenase (NAD+) activity
GO:0005789 - endoplasmic reticulum membrane
GO:0007601 - visual perception

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1349364

RDH11
Retinol dehydrogenase 11

2

15

High-throughput

0.754

High

967343

TSN5
Tetraspanin-5

3

5

High-throughput

0.609

High

1133152

LASP1
LIM and SH3 domain protein 1

3

2

High-throughput

0.609

High

1220746

RN123
E3 ubiquitin-protein ligase RNF123

3

3

High-throughput

0.609

High

1381186

UB2E3
Ubiquitin-conjugating enzyme E2 E3

3

1

High-throughput

0.609

High

1399162

TES
Testin

2

1

High-throughput

0.574

High

1399160

UBE2T
Ubiquitin-conjugating enzyme E2 T

2

2

High-throughput

0.558

High

1234912

PKHA7
Pleckstrin homology domain-containing family A member 7

2

5

High-throughput

0.553

High

564234

CFTR
Cystic fibrosis transmembrane conductance regulator

1

5

High-throughput

0.541

High

1399153

PLCA
1-acyl-sn-glycerol-3-phosphate acyltransferase alpha

1

3

High-throughput

0.536

High

943114

STX17
Syntaxin-17

1

0

High-throughput

0.513

High

248237

NDK8
Putative nucleoside diphosphate kinase

2

2

High-throughput

0.504

High

224156

BUB1
Mitotic checkpoint serine/threonine-protein kinase BUB1

1

3

High-throughput

0.494

High

1399158

MLP3A
Microtubule-associated protein 1 light chain 3 alpha

1

1

High-throughput

0.494

High

349539

TSN15
Tetraspanin-15

1

5

High-throughput

0.489

High

1023860

2ABB
Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform

1

3

High-throughput

0.489

High

1385419

EFHD2
EF-hand domain-containing protein D2

1

4

High-throughput

0.489

High

1399155

PINK1
Serine/threonine-protein kinase PINK1, mitochondrial

1

1

High-throughput

0.489

High

1399157

TTYH1
Protein tweety homolog 1

1

1

High-throughput

0.489

High

1399159

RANB3
Ran-binding protein 3

1

1

High-throughput

0.489

High

508464

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

2

Small-scale

0.479

High

1217676

AXA81
Annexin A8-like protein 1

1

5

High-throughput

0.439

High

294201

CD123
Translation initiation factor eIF2 assembly protein

1

4

High-throughput

0.437

High

912802

AGFG1
Arf-GAP domain and FG repeat-containing protein 1

1

1

High-throughput

0.437

High

982290

UB2D2
Ubiquitin-conjugating enzyme E2 D2

1

1

High-throughput

0.437

High

1399154

UBAC1
Ubiquitin-associated domain-containing protein 1

1

1

High-throughput

0.437

High

568972

ANXA8
Annexin A8

1

5

High-throughput

0.417

High

1399163

ITM2B
Integral membrane protein 2B

1

2

High-throughput

0.407

High

828432

PEX19
Peroxisomal biogenesis factor 19

3

0

High-throughput

0.347

High

1187015

TKFC
Triokinase/FMN cyclase

3

0

High-throughput

0.347

High

1280149

ARPIN
Arpin

3

0

High-throughput

0.347

High

1372040

RBPMS
RNA-binding protein with multiple splicing

2

0

High-throughput

0.341

High

340663

STABP
STAM-binding protein

2

0

High-throughput

0.328

High

1109587

4EBP2
Eukaryotic translation initiation factor 4E-binding protein 2

2

0

High-throughput

0.328

High

325348

OR2A4
Olfactory receptor 2A4

1

0

High-throughput

0.279

Low

733417

CCR1
C-C chemokine receptor type 1

1

0

High-throughput

0.279

Low

748706

CGL
Cystathionine gamma-lyase

1

0

High-throughput

0.279

Low

1143005

PMVK
Phosphomevalonate kinase

1

0

High-throughput

0.279

Low

1181337

CR021
UPF0711 protein C18orf21

1

0

High-throughput

0.279

Low

1292330

ZC3C1
Zinc finger C3HC-type protein 1

1

0

High-throughput

0.279

Low

1391680

PLPP
Chronophin

1

0

High-throughput

0.279

Low

1399156

CHM4A
Charged multivesicular body protein 4a

1

0

High-throughput

0.279

Low

1399161

MBNL1
Muscleblind-like protein 1

1

0

High-throughput

0.279

Low

1399164

SSUH2
Protein SSUH2 homolog

1

0

High-throughput

0.279

Low

1292645

CCD25
Coiled-coil domain-containing protein 25

1

0

High-throughput

0.249

Low

1310749

ARCH
Protein archease

1

0

High-throughput

0.249

Low

1329727

ARFG1
ADP-ribosylation factor GTPase-activating protein 1

1

0

High-throughput

0.249

Low

261252

NSMA
Sphingomyelin phosphodiesterase 2

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025