HitPredict

Interactor 1: DBP4 (P20448)
ATP-dependent RNA helicase HCA4 (EC 3.6.4.13) (DEAD box protein 4) (Helicase CA4) (Helicase UF1)
Gene: HCA4

Interactor 2: HSP7F (P32589)
Heat shock protein homolog SSE1 (Chaperone protein MSI3)
Gene: SSE1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	19536198
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005524 - ATP binding GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 770 Sc			1 693
+	Sc
		593610 DBP4_YEAST (1-770): 3.32e-163: 492: 100.00		HSP79_YEAST (1-677): 0: 992: 77.11
+	Hs
		504840 DDX18_HUMAN (2-537): 5.49e-149: 452: 35.61		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		504506 DDX17_HUMAN (7-450): 2.25e-125: 393: 27.17		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Hs
		503397 DDX5_HUMAN (7-468): 2.47e-122: 382: 26.94		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		624052 DBP2_YEAST (7-435): 1.13e-119: 372: 28.11		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		695407 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Hs
		504735 DDX47_HUMAN (39-405): 2.75e-61: 215: 35.87		HSP7C_HUMAN (2-645): 0: 851: 27.04
+	Sc
		694369 DRS1_YEAST (43-418): 9.8e-52: 194: 32.38		HSP7F_YEAST (1-693): 0: 829: 100.00
+	Sc
		493176 DBP4_YEAST (1-770): 3.32e-163: 492: 100.00		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490310 DBP4_YEAST (1-770): 3.32e-163: 492: 100.00		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		493255 DBP2_YEAST (7-435): 1.13e-119: 372: 28.11		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490410 DBP2_YEAST (7-435): 1.13e-119: 372: 28.11		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		494827 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		492264 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		415870 DED1_YEAST (21-450): 2.97e-114: 360: 26.68		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		493538 DRS1_YEAST (43-418): 9.8e-52: 194: 32.38		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		493332 SPB4_YEAST (55-489): 4.52e-52: 193: 31.36		HSP72_YEAST (1-382): 1.15e-71: 246: 36.82
+	Sc
		490736 DRS1_YEAST (43-418): 9.8e-52: 194: 32.38		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		490494 SPB4_YEAST (55-489): 4.52e-52: 193: 31.36		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55
+	Sc
		491259 DHH1_YEAST (38-415): 1.11e-52: 192: 31.93		HSP71_YEAST (1-382): 7.01e-71: 244: 36.55