HitPredict

Interactor 1: DBP4 (P20448)
ATP-dependent RNA helicase HCA4 (EC 3.6.4.13) (DEAD box protein 4) (Helicase CA4) (Helicase UF1)
Gene: HCA4

Interactor 2: ESF2 (P53743)
Pre-rRNA-processing protein ESF2 (18S rRNA factor 2)
Gene: ESF2

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.672

Property	Details
Experiments	15964808, 29054886, 37968396
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0030490 - maturation of SSU-rRNA GO:0032040 - small-subunit processome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 770 Sc			1 316
+	Hs
		1245892 DDX55_HUMAN (39-589): 7.28e-179: 527: 30.00		ABT1_HUMAN (69-316): 1e-102: 303: 24.02
+	Sc
		864724 HAS1_YEAST (3-491): 5.9e-117: 364: 38.34		ESF2_YEAST (1-316): 4.63e-116: 339: 100.00
+	Hs
		1027944 DDX10_HUMAN (3-764): 1.75e-121: 387: 35.07		ABT1_HUMAN (69-316): 1e-102: 303: 24.02
+	Hs
		1254841 DDX54_HUMAN (14-767): 4.85e-116: 373: 21.26		ABT1_HUMAN (69-316): 1e-102: 303: 24.02
+	Sc
		753040 RRP3_YEAST (43-407): 3.57e-55: 199: 35.15		ESF2_YEAST (1-316): 4.63e-116: 339: 100.00
+	Hs
		1328103 DDX47_HUMAN (39-405): 2.75e-61: 215: 35.87		ABT1_HUMAN (69-316): 1e-102: 303: 24.02
+	Hs
		1333562 DDX31_HUMAN (64-488): 9.9e-58: 213: 32.60		ABT1_HUMAN (69-316): 1e-102: 303: 24.02