Protein: TPPC5
Trafficking protein particle complex subunit 5

Gene: TPPC5, TRAPPC5
Organism: Homo sapiens
Interactions: 94
UniProt ID: Q8IUR0

Gene Ontology (top 5):
GO:0005737 - cytoplasm
GO:0005783 - endoplasmic reticulum
GO:0005829 - cytosol
GO:0006888 - endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0006901 - vesicle coating

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

515711

TPC2B
Trafficking protein particle complex subunit 2B

7

14

Small-scale

0.952

High

221744

TPPC3
Trafficking protein particle complex subunit 3

5

13

Small-scale

0.927

High

1307865

TPPC1
Trafficking protein particle complex subunit 1

3

7

High-throughput

0.871

High

295989

TPC6A
Trafficking protein particle complex subunit 6A

2

6

High-throughput

0.811

High

1286671

TPC6B
Trafficking protein particle complex subunit 6B

2

6

High-throughput

0.811

High

1307856

TPC2L
Trafficking protein particle complex subunit 2-like protein

2

14

High-throughput

0.811

High

1307861

TPPC4
Trafficking protein particle complex subunit 4

2

5

High-throughput

0.811

High

515640

TPC2A
Trafficking protein particle complex subunit 2

2

14

High-throughput

0.759

High

1307844

B2L14
Apoptosis facilitator Bcl-2-like protein 14

4

1

High-throughput

0.699

High

1276031

TPC11
Trafficking protein particle complex subunit 11

3

3

High-throughput

0.675

High

874047

TPC10
Trafficking protein particle complex subunit 10

3

8

Small-scale

0.669

High

332530

CCDB1
Cyclin-D1-binding protein 1

4

0

High-throughput

0.668

High

1307833

TPC12
Trafficking protein particle complex subunit 12

3

2

High-throughput

0.667

High

1214234

KANK4
KN motif and ankyrin repeat domain-containing protein 4

3

1

High-throughput

0.662

High

63863

TPC13
Trafficking protein particle complex subunit 13

2

1

High-throughput

0.628

High

1307839

TPPC9
Trafficking protein particle complex subunit 9

2

4

High-throughput

0.628

High

1307848

STMN4
Stathmin-4

2

1

High-throughput

0.628

High

1307854

TBC14
TBC1 domain family member 14

2

1

High-throughput

0.628

High

1307862

TPPC8
Trafficking protein particle complex subunit 8

2

1

High-throughput

0.628

High

1212062

TPC3L
Trafficking protein particle complex subunit 3-like protein

1

13

Small-scale

0.621

High

1128917

I13R2
Interleukin-13 receptor subunit alpha-2

3

1

High-throughput

0.604

High

1307830

TPC2
Two pore channel protein 2

2

0

High-throughput

0.602

High

1307832

TPC14
Trafficking protein particle complex subunit 14

2

0

High-throughput

0.602

High

593675

BGAL
Beta-galactosidase

1

1

High-throughput

0.536

High

1307859

GAB2
GRB2-associated-binding protein 2

1

1

High-throughput

0.536

High

1307863

MTL5
Tesmin

1

1

High-throughput

0.536

High

445213

S10A6
Protein S100-A6

1

0

High-throughput

0.513

High

922830

ITA8
Integrin alpha-8 [Cleaved into: Integrin alpha-8 heavy chain; Integrin alpha-8 light chain]

1

0

High-throughput

0.513

High

1217701

PRA17
PRAME family member 17

1

0

High-throughput

0.513

High

1307834

AQP3
Aquaporin-3

1

0

High-throughput

0.513

High

1307843

MTND
Acireductone dioxygenase

1

0

High-throughput

0.513

High

1307845

UBXN6
UBX domain-containing protein 6

1

0

High-throughput

0.513

High

1307847

BTBD1
BTB/POZ domain-containing protein 1

1

0

High-throughput

0.513

High

1307860

ERGI3
Endoplasmic reticulum-Golgi intermediate compartment protein 3

1

0

High-throughput

0.513

High

1143186

PLEC
Plectin

1

0

High-throughput

0.493

High

605011

HXB6
Homeobox protein Hox-B6

1

1

High-throughput

0.489

High

1253032

RUFY4
RUN and FYVE domain-containing protein 4

1

1

High-throughput

0.489

High

1295412

RAB43
Ras-related protein Rab-43

1

4

High-throughput

0.489

High

1307864

PCDGD
Protocadherin gamma-B1

1

1

High-throughput

0.489

High

341615

EYA4
Protein phosphatase EYA4

1

1

High-throughput

0.479

High

1033721

PO5F1
POU domain, class 5, transcription factor 1

1

1

High-throughput

0.479

High

1307836

OPTN
Optineurin

1

2

High-throughput

0.479

High

242195

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

315752

RECQ4
ATP-dependent DNA helicase Q4

1

0

High-throughput

0.458

High

363529

EGFR
Epidermal growth factor receptor

1

0

High-throughput

0.458

High

540545

LAMP1
Lysosome-associated membrane glycoprotein 1

1

0

High-throughput

0.458

High

888176

MCM2
DNA replication licensing factor MCM2

1

0

High-throughput

0.458

High

1254509

TRI67
Tripartite motif-containing protein 67

1

0

High-throughput

0.458

High

1307849

PKHA4
Pleckstrin homology domain-containing family A member 4

1

0

High-throughput

0.458

High

1307855

ZRAN1
Ubiquitin thioesterase ZRANB1

1

0

High-throughput

0.458

High

1098720

NDK3
Nucleoside diphosphate kinase 3

1

1

High-throughput

0.445

High

1307840

RAB3I
Rab-3A-interacting protein

1

2

Small-scale

0.445

High

218417

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.437

High

1031443

IFM3
Interferon-induced transmembrane protein 3

1

2

High-throughput

0.437

High

1116239

PTC1
Protein patched homolog 1

1

1

Small-scale

0.437

High

1251921

LMTK1
Serine/threonine-protein kinase LMTK1

1

1

High-throughput

0.437

High

1307851

NANOG
Homeobox protein NANOG

1

1

High-throughput

0.437

High

248905

GSDME
Gasdermin-E

1

0

High-throughput

0.426

High

541038

PIM1
Serine/threonine-protein kinase pim-1

1

0

High-throughput

0.426

High

896410

ERF
ETS domain-containing transcription factor ERF

1

0

High-throughput

0.426

High

1239234

ARMC6
Armadillo repeat-containing protein 6

1

0

High-throughput

0.426

High

1307835

LPAR1
Lysophosphatidic acid receptor 1

1

0

High-throughput

0.426

High

1307837

AURKB
Aurora kinase B

1

0

High-throughput

0.426

High

1307841

TBA1C
Tubulin alpha-1C chain

1

0

High-throughput

0.426

High

1307857

PCDGG
Protocadherin gamma-B4

1

1

High-throughput

0.407

High

1307838

CABS1
Calcium-binding and spermatid-specific protein 1

3

0

High-throughput

0.347

High

332671

LYPD3
Ly6/PLAUR domain-containing protein 3

2

0

High-throughput

0.318

High

1307852

HM20A
High mobility group protein 20A

2

0

High-throughput

0.316

High

1307829

PTGR3
Prostaglandin reductase 3

2

0

High-throughput

0.313

High

369698

A2MG
Alpha-2-macroglobulin

1

0

High-throughput

0.282

High

215870

AN32C
Putative uncharacterized protein ANP32CP

1

0

High-throughput

0.279

Low

879803

NPY2R
Neuropeptide Y receptor type 2

1

0

High-throughput

0.279

Low

1053026

VMAT2
Synaptic vesicular amine transporter

1

0

High-throughput

0.279

Low

1098915

KLRD1
Natural killer cells antigen CD94

1

0

High-throughput

0.279

Low

1142094

P2RY6
P2Y purinoceptor 6

1

0

High-throughput

0.279

Low

1214096

DIK1A
Divergent protein kinase domain 1A

1

0

High-throughput

0.279

Low

1307831

F174A
Membrane protein FAM174A

1

0

High-throughput

0.279

Low

1307846

S22A4
Solute carrier family 22 member 4

1

0

High-throughput

0.279

Low

1307850

MED20
Mediator of RNA polymerase II transcription subunit 20

1

0

High-throughput

0.279

Low

1307853

GTR9
Solute carrier family 2, facilitated glucose transporter member 9

1

0

High-throughput

0.279

Low

420235

IFNA6
Interferon alpha-6

1

0

High-throughput

0.269

Low

589089

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.249

Low

695873

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

0

High-throughput

0.249

Low

768587

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.249

Low

931864

EPHA5
Ephrin type-A receptor 5

1

0

High-throughput

0.249

Low

1276198

ATG9A
Autophagy-related protein 9A

1

0

High-throughput

0.249

Low

1307842

CNPY3
Protein canopy homolog 3

1

0

Small-scale

0.249

Low

1307858

WDR3
WD repeat-containing protein 3

1

0

High-throughput

0.249

Low

255108

HCN1
Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1

1

0

High-throughput

0.232

Low

260903

RAMP3
Receptor activity-modifying protein 3

1

0

High-throughput

0.232

Low

437727

HEPS
Serine protease hepsin

1

0

High-throughput

0.232

Low

942346

BACE1
Beta-secretase 1

1

0

Small-scale

0.232

Low

1063804

LG3BP
Galectin-3-binding protein

1

0

High-throughput

0.232

Low

1307828

CI040
Uncharacterized protein C9orf40

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025