Interactor 1: MSH3 (P20585)
DNA mismatch repair protein Msh3 (hMSH3) (Divergent upstream protein) (DUP) (Mismatch repair protein 1) (MRP1)
Gene: MSH3
Interactor 2: MSH2 (P43246)
DNA mismatch repair protein Msh2 (hMSH2) (MutS protein homolog 2)
Gene: MSH2
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.96 | 1.00 | 0.984 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 10029069, 37140056, 14657349, 9774676, 33961781, 8942985, 21957315, 34591612, 8805365, 19377479, 16025128, 22179786 |
| Identification Methods | pull down, affinity chromatography technology, cosedimentation in solution, ion exchange chromatography, molecular sieving, x-ray crystallography, anti tag coimmunoprecipitation |
| Interaction Type | direct interaction, physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | MutS_I~MutS_I, MutS_I~MutS_II, MutS_I~MutS_III, MutS_I~MutS_V, MutS_II~MutS_III, MutS_II~MutS_V, MutS_III~MutS_III, MutS_III~MutS_V, MutS_V~MutS_V |
| Common GO terms | GO:0005524 - ATP binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006281 - DNA repair GO:0006298 - mismatch repair and 8 others more... |
| Homologous interactions | 13 |
Homologous interactions
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
