HitPredict

Interactor 1: PP11 (P20604)
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)
Gene: SIT4

Interactor 2: PTPA1 (P40454)
Serine/threonine-protein phosphatase 2A activator 1 (EC 5.2.1.8) (Peptidyl-prolyl cis-trans isomerase PTPA-1) (PPIase PTPA-1) (Rotamase PTPA-1) (Phosphotyrosyl phosphatase activator 1)
Gene: RRD1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.88 1.00 0.941

The method score is based on:

Property Details
Experiments 15447631, 15689491, 11134337, 15150670, 21179020, 16429126
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Metallophos~PTPA
Common GO terms GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000159 - protein phosphatase type 2A complex
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006281 - DNA repair
and 1 others

more...
Homologous interactions 11

Homologous interactions

Color coding for hit scores

1 311
Sc

1 393
+ Sc
+ At
+ Mm
+ Hs
+ Hs
+ Hs
+ Mm
+ Hs
+ Dm
+ Sc
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024