HitPredict

Interactor 1: PP11 (P20604)
Serine/threonine-protein phosphatase PP1-1 (EC 3.1.3.16)
Gene: SIT4

Interactor 2: HRK1 (Q08732)
Serine/threonine-protein kinase HRK1 (EC 2.7.11.1) (Hygromycin resistance kinase 1)
Gene: HRK1

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.64	0.60	0.621

Property	Details
Experiments	11805826, 16429126
Identification Methods	tandem affinity purification, affinity chromatography technology
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0035556 - intracellular signal transduction
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 311 Sc			1 759
+	Hs
		682162 PP2AA_HUMAN (1-311): 0: 519: 56.59		AKT2_HUMAN (92-558): 4.1e-131: 399: 14.59
+	Mm
		682104 PP2AA_MOUSE (1-311): 0: 519: 56.59		AKT1_MOUSE (92-540): 6.04e-129: 394: 14.91
+	Hs
		681777 PP2AA_HUMAN (1-311): 0: 519: 56.59		AKT1_HUMAN (92-540): 1.52e-128: 393: 14.91
+	Hs
		931045 PP2AA_HUMAN (1-311): 0: 519: 56.59		AKT3_HUMAN (103-526): 1.02e-125: 385: 16.28
+	Mm
		682103 PP1A_MOUSE (6-305): 0: 507: 42.53		AKT1_MOUSE (92-540): 6.04e-129: 394: 14.91
+	Hs
		681767 PP1A_HUMAN (6-305): 0: 506: 42.86		AKT1_HUMAN (92-540): 1.52e-128: 393: 14.91
+	Hs
		647866 PP2AB_HUMAN (2-311): 0: 520: 57.10		MARK3_HUMAN (160-752): 5.08e-119: 377: 17.05
+	Hs
		681698 PP1G_HUMAN (11-301): 0: 503: 43.73		AKT1_HUMAN (92-540): 1.52e-128: 393: 14.91
+	Hs
		625340 PP2AA_HUMAN (1-311): 0: 519: 56.59		CDK2_HUMAN (211-510): 2.26e-119: 362: 23.95
+	Hs
		625299 PP1A_HUMAN (6-305): 0: 506: 42.86		CDK2_HUMAN (211-510): 2.26e-119: 362: 23.95
+	Hs
		625180 PP1G_HUMAN (11-301): 0: 503: 43.73		CDK2_HUMAN (211-510): 2.26e-119: 362: 23.95
+	Mm
		906391 PP1A_MOUSE (6-305): 0: 507: 42.53		STK39_MOUSE (215-639): 9.79e-103: 328: 19.45