HitPredict

Interactor 1: PSB1 (P20618)
Proteasome subunit beta type-1 (Macropain subunit C5) (Multicatalytic endopeptidase complex subunit C5) (Proteasome component C5) (Proteasome gamma chain)
Gene: PSMB1

Interactor 2: Q5JNW7 (Q5JNW7)
Proteasome 20S subunit beta 8 (Proteasome subunit beta type-8)
Gene: PSMB8

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.34	1.00	0.590

Property	Details
Experiments	14733938
Identification Methods	two hybrid
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Proteasome~Proteasome
Common GO terms	GO:0005634 - nucleus GO:0005839 - proteasome core complex GO:0051603 - proteolysis involved in protein catabolic process
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 241 Hs			1 252
+	Hs
		594453 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB8_HUMAN (1-252): 8.99e-96: 283: 90.58
+	Hs
		656046 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB8_HUMAN (1-252): 8.99e-96: 283: 90.58
+	Hs
		156218 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSA7_HUMAN (48-245): 3.19e-70: 217: 14.59
+	Hs
		594455 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSA5_HUMAN (43-247): 1.81e-69: 215: 12.81
+	Hs
		594448 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSA2_HUMAN (49-248): 7.93e-69: 213: 15.15
+	Hs
		594458 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB5_HUMAN (1-248): 2.39e-68: 213: 50.37
+	Hs
		594591 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSMA8_HUMAN (48-245): 4.64e-68: 212: 13.39
+	Hs
		156251 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSA7_HUMAN (48-245): 3.19e-70: 217: 14.59
+	Hs
		594457 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB6_HUMAN (52-231): 6.48e-67: 209: 29.27
+	Hs
		656173 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSA5_HUMAN (43-247): 1.81e-69: 215: 12.81
+	Hs
		637648 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSA2_HUMAN (49-248): 7.93e-69: 213: 15.15
+	Hs
		656680 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB5_HUMAN (1-248): 2.39e-68: 213: 50.37
+	Hs
		832023 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSMA8_HUMAN (48-245): 4.64e-68: 212: 13.39
+	Hs
		656569 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB6_HUMAN (52-231): 6.48e-67: 209: 29.27
+	Hs
		594454 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB9_HUMAN (54-231): 3.05e-58: 185: 29.21
+	Hs
		594563 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		Q6IBT1_HUMAN (70-240): 1.8e-55: 180: 23.08
+	Hs
		594614 PSB1_HUMAN (1-241): 8.65e-85: 253: 100.00		PSB7_HUMAN (70-240): 1.58e-55: 180: 23.08
+	Hs
		656098 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB9_HUMAN (54-231): 3.05e-58: 185: 29.21
+	Hs
		771441 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		PSB10_HUMAN (70-231): 3.35e-56: 182: 25.81
+	Hs
		832010 PSB3_HUMAN (31-241): 3.45e-82: 246: 23.94		Q6IBT1_HUMAN (70-240): 1.8e-55: 180: 23.08