Protein: MLH3
DNA mismatch repair protein Mlh3 (MutL protein homolog 3)

Gene: MLH3
Organism: Homo sapiens
Interactions: 57
UniProt ID: Q9UHC1

Gene Ontology (top 5):
GO:0000795 - synaptonemal complex
GO:0001673 - male germ cell nucleus
GO:0003682 - chromatin binding
GO:0003696 - satellite DNA binding
GO:0005524 - ATP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

776419

MLH1
DNA mismatch repair protein Mlh1

5

13

Small-scale

0.930

High

179986

MSH4
MutS protein homolog 4

2

20

Small-scale

0.812

High

198167

MSH5
MutS protein homolog 5

1

20

Small-scale

0.647

High

135907

F16P2
Fructose-1,6-bisphosphatase isozyme 2

1

1

High-throughput

0.541

High

239421

CC14B
Dual specificity protein phosphatase CDC14B

1

2

High-throughput

0.541

High

265921

FRAT2
GSK-3-binding protein FRAT2

1

1

High-throughput

0.541

High

349706

RASH
GTPase HRas

1

1

High-throughput

0.541

High

450957

F16P1
Fructose-1,6-bisphosphatase 1

1

1

High-throughput

0.541

High

612509

XPA
DNA repair protein complementing XP-A cells

1

2

High-throughput

0.541

High

682059

AKT1
RAC-alpha serine/threonine-protein kinase

1

1

High-throughput

0.541

High

915298

PP2AB
Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform

1

3

High-throughput

0.541

High

960717

FANCC
Fanconi anemia group C protein

1

1

High-throughput

0.541

High

972267

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

1

3

High-throughput

0.541

High

1048046

CYLC2
Cylicin-2

1

1

High-throughput

0.541

High

1078770

SMAD1
Mothers against decapentaplegic homolog 1

1

1

High-throughput

0.541

High

1269104

AN32B
Acidic leucine-rich nuclear phosphoprotein 32 family member B

1

1

High-throughput

0.541

High

1282067

TRI63
E3 ubiquitin-protein ligase TRIM63

1

3

High-throughput

0.541

High

1317537

TRI55
Tripartite motif-containing protein 55

1

3

High-throughput

0.541

High

1317598

TBD2A
TBC1 domain family member 2A

1

2

High-throughput

0.541

High

1355317

LEF1
Lymphoid enhancer-binding factor 1

1

1

High-throughput

0.541

High

348161

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.536

High

351463

TGFB1
Transforming growth factor beta-1 proprotein [Cleaved into: Latency-associated peptide

1

0

High-throughput

0.518

High

572528

IBP3
Insulin-like growth factor-binding protein 3

1

0

High-throughput

0.518

High

826369

CDK8
Cyclin-dependent kinase 8

1

0

High-throughput

0.518

High

1315454

HEMGN
Hemogen

1

0

High-throughput

0.518

High

1355319

ZN510
Zinc finger protein 510

1

0

High-throughput

0.518

High

1191617

SPRE1
Sprouty-related, EVH1 domain-containing protein 1

1

1

High-throughput

0.515

High

517526

PCNA
Proliferating cell nuclear antigen

1

5

Small-scale

0.501

High

1355318

EXO1
Exonuclease 1

1

5

Small-scale

0.501

High

245853

CATL2
Cathepsin L2

1

1

High-throughput

0.494

High

393831

ALDOB
Fructose-bisphosphate aldolase B

1

2

High-throughput

0.494

High

596440

RASA1
Ras GTPase-activating protein 1

1

1

High-throughput

0.494

High

739568

DHB3
17-beta-hydroxysteroid dehydrogenase type 3

1

1

High-throughput

0.494

High

882828

STX17
Syntaxin-17

1

1

High-throughput

0.494

High

1047990

BAAT
Bile acid-CoA:amino acid N-acyltransferase

1

1

High-throughput

0.494

High

1220932

GLT12
Polypeptide N-acetylgalactosaminyltransferase 12

1

2

High-throughput

0.494

High

1245988

TDRD7
Tudor domain-containing protein 7

1

1

High-throughput

0.494

High

1293534

SFRP2
Secreted frizzled-related protein 2

1

1

High-throughput

0.494

High

1347816

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

1

0

High-throughput

0.493

High

487819

ANDR
Androgen receptor

1

1

Small-scale

0.481

High

164498

TRI66
Tripartite motif-containing protein 66

1

3

High-throughput

0.479

High

1042771

CUL3
Cullin-3

1

3

High-throughput

0.479

High

1222627

SLX4
Structure-specific endonuclease subunit SLX4

1

3

High-throughput

0.479

High

1355320

FAN1
Fanconi-associated nuclease 1

1

6

Small-scale

0.479

High

103864

G5E9A7
DM1 locus, WD repeat containing

1

3

High-throughput

0.470

High

73236

B4DZK1
cDNA FLJ50036, weakly similar to Myosin-11

1

5

High-throughput

0.439

High

1349967

CC180
Coiled-coil domain-containing protein 180

1

5

High-throughput

0.417

High

150761

DVL1
Segment polarity protein dishevelled homolog DVL-1

1

0

High-throughput

0.282

High

657559

TMOD1
Tropomodulin-1

1

0

High-throughput

0.282

High

890496

SC61B
Protein transport protein Sec61 subunit beta

1

0

High-throughput

0.282

High

1135035

TSTD2
Thiosulfate sulfurtransferase/rhodanese-like domain-containing protein 2

1

0

High-throughput

0.282

High

1216590

ZDH17
Palmitoyltransferase ZDHHC17

1

0

High-throughput

0.282

High

1223505

TEFF1
Tomoregulin-1

1

0

High-throughput

0.282

High

1236179

AMPO
Aminopeptidase O

1

0

High-throughput

0.282

High

1292985

MSD3
Myb/SANT-like DNA-binding domain-containing protein 3

1

0

High-throughput

0.282

High

1297569

CANB2
Calcineurin subunit B type 2

1

0

High-throughput

0.282

High

1344247

SIAS
Sialic acid synthase

1

0

High-throughput

0.282

High


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Last updated: 15 Jul 2024