HitPredict

Interactor 1: H2A1D (P20671)
Histone H2A type 1-D (Histone H2A.3) (Histone H2A/g)
Gene: H2AC7

Interactor 2: CENPA (P49450)
Histone H3-like centromeric protein A (Centromere autoantigen A) (Centromere protein A) (CENP-A)
Gene: CENPA

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	1.00	0.575

Property	Details
Experiments	15009096
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	Histone~Histone, Histone~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 130 Hs			1 140
+	Hs
		391597 H2A1B_HUMAN (1-130): 1.21e-67: 201: 99.23		CENPA_HUMAN (1-140): 2.13e-55: 171: 100.00
+	Hs
		470336 H2A1_HUMAN (1-130): 9.38e-68: 202: 99.23		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		934877 H2A2A_HUMAN (1-130): 7.05e-68: 202: 97.69		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		391649 H2A1B_HUMAN (1-130): 1.21e-67: 201: 99.23		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		1086182 H2A2A_HUMAN (1-130): 7.05e-68: 202: 97.69		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		1086192 H2A3_HUMAN (1-130): 8.98e-68: 202: 98.46		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		470399 H2A1_HUMAN (1-130): 9.38e-68: 202: 99.23		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		935170 H2A1J_HUMAN (1-128): 3.1e-67: 200: 98.44		H31_HUMAN (5-134): 1.29e-52: 164: 48.86
+	Hs
		1151344 H2A2A_HUMAN (1-130): 7.05e-68: 202: 97.69		H32_HUMAN (5-134): 1.73e-51: 161: 48.86
+	Hs
		1174619 H2A1C_HUMAN (1-130): 8.59e-68: 202: 97.69		H32_HUMAN (5-134): 1.73e-51: 161: 48.86
+	Hs
		391723 H2A1B_HUMAN (1-130): 1.21e-67: 201: 99.23		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		470350 H2A1_HUMAN (1-130): 9.38e-68: 202: 99.23		H33_HUMAN (5-134): 1.57e-51: 161: 49.62
+	Hs
		470427 H2A1_HUMAN (1-130): 9.38e-68: 202: 99.23		H32_HUMAN (5-134): 1.73e-51: 161: 48.86
+	Hs
		1086278 H2A1H_HUMAN (1-128): 4.97e-67: 200: 99.22		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		1086293 H2A1J_HUMAN (1-128): 3.1e-67: 200: 98.44		H31T_HUMAN (5-134): 1.01e-51: 162: 48.09
+	Hs
		391655 H2A1B_HUMAN (1-130): 1.21e-67: 201: 99.23		H33_HUMAN (5-134): 1.57e-51: 161: 49.62
+	Hs
		391757 H2A1B_HUMAN (1-130): 1.21e-67: 201: 99.23		H32_HUMAN (5-134): 1.73e-51: 161: 48.86
+	Hs
		1174631 H2A1H_HUMAN (1-128): 4.97e-67: 200: 99.22		H32_HUMAN (5-134): 1.73e-51: 161: 48.86
+	Hs
		470413 H2A1_HUMAN (1-130): 9.38e-68: 202: 99.23		H37_HUMAN (5-134): 1.18e-49: 156: 47.33
+	Hs
		391740 H2A1B_HUMAN (1-130): 1.21e-67: 201: 99.23		H37_HUMAN (5-134): 1.18e-49: 156: 47.33