Protein: PAXB1
PAX3- and PAX7-binding protein 1 (GC-rich sequence DNA-binding factor 1)

Gene: PAXB1, PAXBP1
Organism: Homo sapiens
Interactions: 103
UniProt ID: Q9Y5B6

Gene Ontology (top 5):
GO:0000398 - mRNA splicing, via spliceosome
GO:0003677 - DNA binding
GO:0005634 - nucleus
GO:0005829 - cytosol
GO:0006366 - transcription by RNA polymerase II

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1387303

HDA11
Histone deacetylase 11

4

1

High-throughput

0.697

High

1387664

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

4

1

High-throughput

0.694

High

1414637

DDX23
Probable ATP-dependent RNA helicase DDX23

4

1

High-throughput

0.694

High

974095

RUXF
Small nuclear ribonucleoprotein F

3

1

High-throughput

0.675

High

1394569

RSRC1
Serine/Arginine-related protein 53

3

0

High-throughput

0.638

High

574534

RSMB
Small nuclear ribonucleoprotein-associated proteins B and B'

2

2

High-throughput

0.628

High

973859

RUXE
Small nuclear ribonucleoprotein E

2

1

High-throughput

0.628

High

991278

RSMN
Small nuclear ribonucleoprotein-associated protein N

2

2

High-throughput

0.628

High

1006830

SRPK2
SRSF protein kinase 2

2

1

High-throughput

0.628

High

974224

RUXG
Small nuclear ribonucleoprotein G

2

5

High-throughput

0.611

High

1138819

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

1

High-throughput

0.611

High

1239700

JMJD6
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6

2

0

High-throughput

0.602

High

1491518

TSSC4
U5 small nuclear ribonucleoprotein TSSC4

2

0

High-throughput

0.585

High

397324

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

335944

CD2B2
CD2 antigen cytoplasmic tail-binding protein 2

1

1

High-throughput

0.536

High

478275

SNRPA
U1 small nuclear ribonucleoprotein A

1

1

High-throughput

0.536

High

485769

RU2A
U2 small nuclear ribonucleoprotein A'

1

1

High-throughput

0.536

High

974302

LSM3
U6 snRNA-associated Sm-like protein LSm3

1

3

High-throughput

0.536

High

974879

SMD3
Small nuclear ribonucleoprotein Sm D3

1

1

High-throughput

0.536

High

1062163

SRSF4
Serine/arginine-rich splicing factor 4

1

1

High-throughput

0.536

High

1099619

SRSF6
Serine/arginine-rich splicing factor 6

1

1

High-throughput

0.536

High

1462460

SRPK3
SRSF protein kinase 3

1

1

High-throughput

0.536

High

257289

PQBP1
Polyglutamine-binding protein 1

1

0

High-throughput

0.513

High

286125

SF3B1
Splicing factor 3B subunit 1

1

0

High-throughput

0.513

High

480368

RU1C
U1 small nuclear ribonucleoprotein C

1

0

High-throughput

0.513

High

531184

KAP0
cAMP-dependent protein kinase type I-alpha regulatory subunit

1

0

High-throughput

0.513

High

854403

KI67
Proliferation marker protein Ki-67

1

0

High-throughput

0.513

High

879769

MAPK2
MAP kinase-activated protein kinase 2

1

0

High-throughput

0.513

High

1149240

SF3A1
Splicing factor 3A subunit 1

1

0

High-throughput

0.513

High

1394122

GPTC3
G patch domain-containing protein 3

1

0

High-throughput

0.513

High

1461788

TPX2
Targeting protein for Xklp2

1

0

High-throughput

0.513

High

1127288

RBM39
RNA-binding protein 39

1

1

High-throughput

0.489

High

289740

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

4

High-throughput

0.479

High

320186

UFL1
E3 UFM1-protein ligase 1

1

1

High-throughput

0.479

High

331448

KI20A
Kinesin-like protein KIF20A

1

1

High-throughput

0.479

High

373615

MYC
Myc proto-oncogene protein

1

1

High-throughput

0.479

High

401766

RAF1
RAF proto-oncogene serine/threonine-protein kinase

1

1

High-throughput

0.479

High

406851

MYCN
N-myc proto-oncogene protein

1

1

High-throughput

0.479

High

520485

ANDR
Androgen receptor

1

2

High-throughput

0.479

High

590137

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.479

High

696978

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

1022819

XIAP
E3 ubiquitin-protein ligase XIAP

1

1

High-throughput

0.479

High

1048144

TLE3
Transducin-like enhancer protein 3

1

2

High-throughput

0.479

High

1088643

CHD3
Chromodomain-helicase-DNA-binding protein 3

1

1

High-throughput

0.479

High

1107377

BIRC3
Baculoviral IAP repeat-containing protein 3

1

1

High-throughput

0.479

High

1128165

DHX8
ATP-dependent RNA helicase DHX8

1

3

High-throughput

0.479

High

1133076

CHD4
Chromodomain-helicase-DNA-binding protein 4

1

1

High-throughput

0.479

High

1241872

PRP8
Pre-mRNA-processing-splicing factor 8

1

2

High-throughput

0.479

High

1311902

DHX40
Probable ATP-dependent RNA helicase DHX40

1

3

High-throughput

0.479

High

1339072

NUP43
Nucleoporin Nup43

1

2

High-throughput

0.479

High

1367690

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1459457

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.479

High

1462374

PPIE
Peptidyl-prolyl cis-trans isomerase E

1

1

High-throughput

0.479

High

1450700

DJC17
DnaJ homolog subfamily C member 17

1

1

High-throughput

0.470

High

129597

MEN1
Menin

1

0

High-throughput

0.458

High

158036

CTRO
Citron Rho-interacting kinase

1

0

High-throughput

0.458

High

326121

UBR5
E3 ubiquitin-protein ligase UBR5

1

0

High-throughput

0.458

High

343120

HERC2
E3 ubiquitin-protein ligase HERC2

1

0

High-throughput

0.458

High

473223

RU17
U1 small nuclear ribonucleoprotein 70 kDa

1

0

High-throughput

0.458

High

766060

BMI1
Polycomb complex protein BMI-1

1

0

High-throughput

0.458

High

879668

NR2C2
Nuclear receptor subfamily 2 group C member 2

1

0

High-throughput

0.458

High

905342

MECP2
Methyl-CpG-binding protein 2

1

0

High-throughput

0.458

High

971361

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

980612

H4
Histone H4

1

0

High-throughput

0.458

High

995919

ACTC
Actin, alpha cardiac muscle 1

1

0

High-throughput

0.458

High

1005434

SERB
Phosphoserine phosphatase

1

0

High-throughput

0.458

High

1024963

VIGLN
Vigilin

1

0

High-throughput

0.458

High

1045951

TF65
Transcription factor p65

1

0

High-throughput

0.458

High

1137612

SUZ12
Polycomb protein SUZ12

1

0

High-throughput

0.458

High

1141112

KIF14
Kinesin-like protein KIF14

1

0

High-throughput

0.458

High

1145851

IRF4
Interferon regulatory factor 4

1

0

High-throughput

0.458

High

1150033

TERF2
Telomeric repeat-binding factor 2

1

0

High-throughput

0.458

High

1155951

EZH2
Histone-lysine N-methyltransferase EZH2

1

0

High-throughput

0.458

High

1287034

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

0

Small-scale

0.458

High

1313573

SMC5
Structural maintenance of chromosomes protein 5

1

0

High-throughput

0.458

High

1352870

DOT1L
Histone-lysine N-methyltransferase, H3 lysine-79 specific

1

0

High-throughput

0.458

High

1368920

RBP56
TATA-binding protein-associated factor 2N

1

0

High-throughput

0.458

High

1393877

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.458

High

1407980

ANM1
Protein arginine N-methyltransferase 1

1

0

High-throughput

0.458

High

1411781

RIOK1
Serine/threonine-protein kinase RIO1

1

0

High-throughput

0.458

High

1438110

RC3H2
Roquin-2

1

0

High-throughput

0.458

High

1449265

RAD18
E3 ubiquitin-protein ligase RAD18

1

0

High-throughput

0.458

High

1452495

TE2IP
Telomeric repeat-binding factor 2-interacting protein 1

1

0

High-throughput

0.458

High

71630

RUXGL
Putative small nuclear ribonucleoprotein G-like protein 15

1

5

High-throughput

0.445

High

207690

DHX15
ATP-dependent RNA helicase DHX15

1

2

Small-scale

0.445

High

1145454

RNPS1
RNA-binding protein with serine-rich domain 1

1

2

High-throughput

0.445

High

1458263

TFP11
Tuftelin-interacting protein 11

1

2

Small-scale

0.445

High

1448598

DISC1
Disrupted in schizophrenia 1 protein

1

0

High-throughput

0.438

High

769620

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

1256266

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1461735

HECD1
E3 ubiquitin-protein ligase HECTD1

1

1

High-throughput

0.437

High

430562

JUN
Transcription factor Jun

1

0

High-throughput

0.426

High

1034550

TAGL
Transgelin

1

0

High-throughput

0.426

High

50130

S22AN
Solute carrier family 22 member 23

2

0

High-throughput

0.328

High

1383614

K1143
Uncharacterized protein KIAA1143

2

0

High-throughput

0.328

High

1395096

JPH4
Junctophilin-4

2

0

High-throughput

0.328

High

1092845

MALL
MAL-like protein

1

0

High-throughput

0.279

Low

1384165

ARRD3
Arrestin domain-containing protein 3

1

0

High-throughput

0.279

Low

1384740

I27L1
Interferon alpha-inducible protein 27-like protein 1

1

0

High-throughput

0.279

Low

1390273

NRBF2
Nuclear receptor-binding factor 2

1

0

High-throughput

0.279

Low

219055

CAC1G
Voltage-dependent T-type calcium channel subunit alpha-1G

1

0

High-throughput

0.249

Low

1290866

ZCH18
Zinc finger CCCH domain-containing protein 18

1

0

High-throughput

0.249

Low

1295645

MYLK4
Myosin light chain kinase family member 4

1

0

High-throughput

0.249

Low


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Last updated: 11Aug2025