HitPredict

Interactor 1: NUP1 (P20676)
Nucleoporin NUP1 (Nuclear pore protein NUP1)
Gene: NUP1

Interactor 2: SPT7 (P35177)
Transcriptional activator SPT7
Gene: SPT7

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21734642
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1076 Sc			1 1332
+	Hs
		1262846 SRRM2_HUMAN (12-1011): 1.73e-11: 71: 7.75		PHIP_HUMAN (234-918): 2.13e-75: 278: 12.26
+	Dm
		1370354 Q9VLS7_DROME (126-1063): 5.48e-19: 95.6: 8.93		NU301_DROME (117-553): 1.31e-65: 248: 13.32
+	Mm
		101493 BICRA_MOUSE (16-972): 7.83e-14: 78.7: 8.22		SMCA2_MOUSE (199-609): 2.45e-65: 246: 10.66
+	Mm
		101492 BICRA_MOUSE (16-972): 7.83e-14: 78.7: 8.22		SMCA4_MOUSE (199-590): 4.14e-63: 239: 11.57
+	Mm
		1150289 SRRM2_MOUSE (11-1071): 2.23e-10: 67.5: 9.65		SMCA2_MOUSE (199-609): 2.45e-65: 246: 10.66
+	Mm
		1111946 SRRM2_MOUSE (11-1071): 2.23e-10: 67.5: 9.65		SMCA4_MOUSE (199-590): 4.14e-63: 239: 11.57
+	Hs
		624815 RPB1_HUMAN (16-391): 2.95e-10: 66.7: 10.10		SMCA2_HUMAN (199-630): 4.71e-62: 236: 11.06
+	Hs
		624816 RPB1_HUMAN (16-391): 2.95e-10: 66.7: 10.10		SMCA4_HUMAN (199-590): 5.78e-62: 235: 11.04
+	Hs
		1342844 SRRM2_HUMAN (12-1011): 1.73e-11: 71: 7.75		BRD7_HUMAN (341-931): 1.06e-58: 217: 12.89
+	Hs
		1342863 PRC2C_HUMAN (32-972): 3.61e-10: 66.7: 9.39		BRD7_HUMAN (341-931): 1.06e-58: 217: 12.89
+	Hs
		858023 NUP98_HUMAN (204-882): 2.45e-12: 73.8: 14.55		CBP_HUMAN (330-549): 7.1e-40: 164: 18.94
+	Hs
		1170076 SRCAP_HUMAN (458-1071): 9.85e-11: 68.7: 9.12		CBP_HUMAN (330-549): 7.1e-40: 164: 18.94
+	Hs
		152675 KMT2D_HUMAN (11-823): 2.15e-10: 67.5: 9.35		CBP_HUMAN (330-549): 7.1e-40: 164: 18.94
+	Hs
		624977 RPB1_HUMAN (16-391): 2.95e-10: 66.7: 10.10		CBP_HUMAN (330-549): 7.1e-40: 164: 18.94
+	Hs
		319122 RPB1_HUMAN (16-391): 2.95e-10: 66.7: 10.10		BRD1_HUMAN (391-697): 9.23e-37: 153: 16.67
+	Hs
		624979 RPB1_HUMAN (16-391): 2.95e-10: 66.7: 10.10		KAT2B_HUMAN (429-544): 6.55e-37: 152: 26.72
+	Dm
		532749 Q9VLS7_DROME (126-1063): 5.48e-19: 95.6: 8.93		FSH_DROME (451-621): 7.99e-15: 82.2: 23.70
+	Sc
		541917 NSP1_YEAST (511-1032): 4.79e-13: 75.7: 16.10		GCN5_YEAST (435-548): 5.76e-20: 96.4: 29.83
+	Hs
		625089 RPB1_HUMAN (16-391): 2.95e-10: 66.7: 10.10		BAZ1B_HUMAN (415-588): 7.47e-17: 88.7: 23.56
+	Hs
		1067200 SRRM2_HUMAN (12-1011): 1.73e-11: 71: 7.75		BRD3_HUMAN (449-548): 2.85e-14: 79.9: 29.81