HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: PML (P29590)
Protein PML (E3 SUMO-protein ligase PML) (EC 2.3.2.-) (Promyelocytic leukemia protein) (RING finger protein 71) (RING-type E3 SUMO transferase PML) (Tripartite motif-containing protein 19) (TRIM19)
Gene: PML

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0016363 - nuclear matrix GO:0031965 - nuclear membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 586 Hs			1 882
+	Hs
		359683 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		PML_HUMAN (1-882): 0: 902: 100.00
+	Hs
		443349 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		PML_HUMAN (1-882): 0: 902: 100.00
+	Hs
		380469 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		TRI26_HUMAN (45-399): 8.61e-52: 192: 12.87
+	Hs
		170252 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		TIF1A_HUMAN (27-546): 1.94e-62: 231: 16.49
+	Hs
		359910 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97
+	Hs
		584872 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		RO52_HUMAN (44-414): 8.03e-56: 202: 13.46
+	Hs
		360442 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TRI39_HUMAN (48-434): 3.1e-57: 207: 11.37
+	Mm
		821713 LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37		TIF1B_MOUSE (46-593): 3.48e-55: 207: 13.37
+	Hs
		359651 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		RO52_HUMAN (44-414): 8.03e-56: 202: 13.46
+	Hs
		62675 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TRI64_HUMAN (48-415): 7.27e-54: 195: 14.32
+	Hs
		975756 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		TRIM1_HUMAN (48-412): 7.57e-53: 199: 14.67
+	Hs
		359894 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TRI26_HUMAN (45-399): 8.61e-52: 192: 12.87
+	Hs
		360383 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		TRIM6_HUMAN (45-465): 1.09e-51: 190: 12.03
+	Hs
		318903 K2C75_HUMAN (4-391): 1.8e-50: 184: 20.61		TRIM1_HUMAN (48-412): 7.57e-53: 199: 14.67
+	Hs
		281082 KRT38_HUMAN (31-407): 1.45e-25: 111: 28.23		TRI33_HUMAN (56-558): 4.27e-74: 265: 15.56
+	Hs
		443490 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		TIF1B_HUMAN (7-593): 6.89e-69: 247: 13.97
+	Hs
		170189 KRT38_HUMAN (31-407): 1.45e-25: 111: 28.23		TIF1A_HUMAN (27-546): 1.94e-62: 231: 16.49
+	Hs
		443320 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		RO52_HUMAN (44-414): 8.03e-56: 202: 13.46
+	Hs
		443583 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		TRI68_HUMAN (43-408): 1.41e-53: 195: 12.37
+	Hs
		443833 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		TRI36_HUMAN (55-384): 5.81e-17: 87.9: 18.51