Protein: S12A9
Solute carrier family 12 member 9 (Cation-chloride cotransporter 6) (hCCC6) (Cation-chloride cotransporter-interacting protein 1) (CCC-interacting protein 1) (hCIP1) (Potassium-chloride transporter 9) (WO3.3)

Gene: S12A9, SLC12A9
Organism: Homo sapiens
Interactions: 208
UniProt ID: Q9BXP2

Gene Ontology (top 5):
GO:0005765 - lysosomal membrane
GO:0005886 - plasma membrane
GO:0006884 - cell volume homeostasis
GO:0015377 - chloride:monoatomic cation symporter activity
GO:0015379 - potassium:chloride symporter activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

127392

LEG8
Galectin-8

3

20

High-throughput

0.667

High

1155182

EREP1
Endosomal transmembrane epsin interactor 1

3

4

High-throughput

0.667

High

1351229

MCLN3
Mucolipin-3

3

1

High-throughput

0.667

High

1417152

POPD2
Popeye domain-containing protein 2

3

3

High-throughput

0.650

High

276251

SEM7A
Semaphorin-7A

2

1

High-throughput

0.628

High

845538

PI2R
Prostacyclin receptor

2

8

High-throughput

0.628

High

1157139

KCA10
Potassium voltage-gated channel subfamily A member 10

2

1

High-throughput

0.628

High

1316364

AGRG5
Adhesion G-protein coupled receptor G5

2

10

High-throughput

0.628

High

1406356

GPR21
Probable G-protein coupled receptor 21

2

8

High-throughput

0.628

High

1417142

NMUR2
Neuromedin-U receptor 2

2

9

High-throughput

0.628

High

1417162

C5AR2
C5a anaphylatoxin chemotactic receptor 2

2

20

High-throughput

0.628

High

1042781

PTH1R
Parathyroid hormone/parathyroid hormone-related peptide receptor

2

13

High-throughput

0.611

High

1292020

TPRA1
Transmembrane protein adipocyte-associated 1

2

0

High-throughput

0.602

High

1417150

MANS1
MANSC domain-containing protein 1

2

0

High-throughput

0.602

High

595104

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

1

High-throughput

0.601

High

609792

LEG3
Galectin-3

2

20

High-throughput

0.601

High

1411140

ZNT2
Proton-coupled zinc antiporter SLC30A2

2

2

High-throughput

0.601

High

926842

VMAT1
Chromaffin granule amine transporter

2

11

High-throughput

0.574

High

132655

UPK1A
Uroplakin-1a

1

13

High-throughput

0.536

High

248506

O10H2
Olfactory receptor 10H2

1

11

High-throughput

0.536

High

537836

HSP7C
Heat shock cognate 71 kDa protein

1

14

High-throughput

0.536

High

868309

P2RY1
P2Y purinoceptor 1

1

18

High-throughput

0.536

High

1007895

X3CL1
Fractalkine

1

1

High-throughput

0.536

High

1036684

APBA1
Amyloid-beta A4 precursor protein-binding family A member 1

1

1

High-throughput

0.536

High

1057580

ACHD
Acetylcholine receptor subunit delta

1

5

High-throughput

0.536

High

1101654

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

17

High-throughput

0.536

High

1195459

NKAI1
Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 1

1

2

High-throughput

0.536

High

1203788

TTMP
TPA-induced transmembrane protein

1

4

High-throughput

0.536

High

1219679

TM268
Transmembrane protein 268

1

2

High-throughput

0.536

High

1328491

M4A15
Membrane-spanning 4-domains subfamily A member 15

1

4

High-throughput

0.536

High

1333598

SIDT2
SID1 transmembrane family member 2

1

2

High-throughput

0.536

High

1339947

OR4N2
Olfactory receptor 4N2

1

9

High-throughput

0.536

High

1392582

S41A3
Solute carrier family 41 member 3

1

2

High-throughput

0.536

High

1417147

TTYH1
Protein tweety homolog 1

1

5

High-throughput

0.536

High

1417153

RXFP1
Relaxin receptor 1

1

5

High-throughput

0.536

High

952511

CTXN1
Cortexin-1

1

0

High-throughput

0.513

High

1399051

TMM74
Transmembrane protein 74

1

0

High-throughput

0.513

High

1403499

KCNKG
Potassium channel subfamily K member 16

1

0

High-throughput

0.513

High

1417141

ASPC1
Tether containing UBX domain for GLUT4

1

0

High-throughput

0.513

High

170942

CLGN
Calmegin

2

11

High-throughput

0.504

High

49817

CLRN2
Clarin-2

1

3

High-throughput

0.489

High

1392293

ZDH12
Palmitoyltransferase ZDHHC12

1

8

High-throughput

0.489

High

157808

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

178384

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.479

High

1249188

LMBRL
Protein LMBR1L

1

2

High-throughput

0.479

High

1417168

ACHA9
Neuronal acetylcholine receptor subunit alpha-9

1

5

High-throughput

0.479

High

130228

PGRC1
Membrane-associated progesterone receptor component 1

1

2

High-throughput

0.445

High

165643

SCAM3
Secretory carrier-associated membrane protein 3

1

6

High-throughput

0.445

High

166997

MGST3
Glutathione S-transferase 3, mitochondrial

1

2

High-throughput

0.445

High

175419

PLXB2
Plexin-B2

1

3

High-throughput

0.445

High

226450

SNG2
Synaptogyrin-2

1

3

High-throughput

0.445

High

248938

GSDME
Gasdermin-E

1

1

High-throughput

0.445

High

295873

FACE1
CAAX prenyl protease 1 homolog

1

1

High-throughput

0.445

High

321344

ERLN2
Erlin-2

1

7

High-throughput

0.445

High

331597

KIF4A
Chromosome-associated kinesin KIF4A

1

1

High-throughput

0.445

High

333171

VAPB
Vesicle-associated membrane protein-associated protein B/C

1

6

High-throughput

0.445

High

350412

ABHGA
Phosphatidylserine lipase ABHD16A

1

4

High-throughput

0.445

High

354171

CLPT1
Putative lipid scramblase CLPTM1

1

2

High-throughput

0.445

High

360101

NB5R3
NADH-cytochrome b5 reductase 3

1

5

High-throughput

0.445

High

417724

RPN1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1

1

4

High-throughput

0.445

High

418412

RPN2
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2

1

4

High-throughput

0.445

High

431891

ITB1
Integrin beta-1

1

3

High-throughput

0.445

High

488853

FURIN
Furin

1

2

High-throughput

0.445

High

540655

LAMP1
Lysosome-associated membrane glycoprotein 1

1

14

High-throughput

0.445

High

596706

NCPR
NADPH--cytochrome P450 reductase

1

4

High-throughput

0.445

High

630956

RAB4A
Ras-related protein Rab-4A

1

20

High-throughput

0.445

High

634610

LMNB1
Lamin-B1

1

2

High-throughput

0.445

High

641004

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

3

High-throughput

0.445

High

699074

CALX
Calnexin

1

11

High-throughput

0.445

High

766817

PHB1
Prohibitin 1

1

4

High-throughput

0.445

High

790177

PIGA
Phosphatidylinositol N-acetylglucosaminyltransferase subunit A

1

2

High-throughput

0.445

High

807564

IF4A3
Eukaryotic initiation factor 4A-III

1

1

High-throughput

0.445

High

813205

OST48
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit

1

2

High-throughput

0.445

High

846666

MSH2
DNA mismatch repair protein Msh2

1

1

High-throughput

0.445

High

852840

VDAC2
Non-selective voltage-gated ion channel VDAC2

1

3

High-throughput

0.445

High

867676

GPR12
G-protein coupled receptor 12

1

7

High-throughput

0.445

High

868064

OR1D4
Olfactory receptor 1D4

1

5

High-throughput

0.445

High

888984

TMEDA
Transmembrane emp24 domain-containing protein 10

1

10

High-throughput

0.445

High

895028

EMD
Emerin

1

2

High-throughput

0.445

High

901018

RAB5C
Ras-related protein Rab-5C

1

20

High-throughput

0.445

High

901544

RAB7A
Ras-related protein Rab-7a

1

20

High-throughput

0.445

High

902042

RAB9A
Ras-related protein Rab-9A

1

20

High-throughput

0.445

High

904103

BAP31
B-cell receptor-associated protein 31

1

3

High-throughput

0.445

High

955999

RAB8A
Ras-related protein Rab-8A

1

10

High-throughput

0.445

High

956469

RAB2A
Ras-related protein Rab-2A

1

20

High-throughput

0.445

High

956608

RAB5B
Ras-related protein Rab-5B

1

20

High-throughput

0.445

High

956781

RAB10
Ras-related protein Rab-10

1

10

High-throughput

0.445

High

957002

CXCR4
C-X-C chemokine receptor type 4

1

17

High-throughput

0.445

High

958009

RAB14
Ras-related protein Rab-14

1

20

High-throughput

0.445

High

976531

RB11A
Ras-related protein Rab-11A

1

9

High-throughput

0.445

High

981348

RAB1A
Ras-related protein Rab-1A

1

11

High-throughput

0.445

High

1009882

NUCB2
Nucleobindin-2

1

1

High-throughput

0.445

High

1015737

RHOG
Rho-related GTP-binding protein RhoG

1

20

High-throughput

0.445

High

1053832

KDSR
3-ketodihydrosphingosine reductase

1

3

High-throughput

0.445

High

1090002

LMAN2
Vesicular integral-membrane protein VIP36

1

6

High-throughput

0.445

High

1105870

TMED1
Transmembrane emp24 domain-containing protein 1

1

15

High-throughput

0.445

High

1122652

MLEC
Malectin

1

1

High-throughput

0.445

High

1132326

GOGB1
Golgin subfamily B member 1

1

1

High-throughput

0.445

High

1141905

EEA1
Early endosome antigen 1

1

4

High-throughput

0.445

High

1143783

PON2
Serum paraoxonase/arylesterase 2

1

1

High-throughput

0.445

High

1146623

TMED2
Transmembrane emp24 domain-containing protein 2

1

12

High-throughput

0.445

High

1164163

CP51A
Lanosterol 14-alpha demethylase

1

8

High-throughput

0.445

High

1164544

MIC60
MICOS complex subunit MIC60

1

1

High-throughput

0.445

High

1207895

S27A3
Long-chain fatty acid transport protein 3

1

6

High-throughput

0.445

High

1275406

ERMP1
Endoplasmic reticulum metallopeptidase 1

1

4

High-throughput

0.445

High

1281760

T179B
Transmembrane protein 179B

1

1

High-throughput

0.445

High

1286296

GALT7
N-acetylgalactosaminyltransferase 7

1

10

High-throughput

0.445

High

1324307

GHDC
GH3 domain-containing protein

1

1

High-throughput

0.445

High

1326572

PP4P2
Type 2 phosphatidylinositol 4,5-bisphosphate 4-phosphatase

1

2

High-throughput

0.445

High

1330381

EMC1
ER membrane protein complex subunit 1

1

2

High-throughput

0.445

High

1340236

MSPD2
Motile sperm domain-containing protein 2

1

6

High-throughput

0.445

High

1348308

GOGA5
Golgin subfamily A member 5

1

6

High-throughput

0.445

High

1349032

DJB14
DnaJ homolog subfamily B member 14

1

14

High-throughput

0.445

High

1356534

RAB2B
Ras-related protein Rab-2B

1

20

High-throughput

0.445

High

1366212

LPAR1
Lysophosphatidic acid receptor 1

1

10

High-throughput

0.445

High

1384759

ARL8A
ADP-ribosylation factor-like protein 8A

1

11

High-throughput

0.445

High

1404183

SEC62
Translocation protein SEC62

1

5

High-throughput

0.445

High

1408196

RNF5
E3 ubiquitin-protein ligase RNF5

1

5

High-throughput

0.445

High

1412647

ESYT1
Extended synaptotagmin-1

1

5

High-throughput

0.445

High

1414880

VAMP8
Vesicle-associated membrane protein 8

1

7

High-throughput

0.445

High

1417144

RAB1B
Ras-related protein Rab-1B

1

9

High-throughput

0.445

High

1417145

LMA2L
VIP36-like protein

1

6

High-throughput

0.445

High

1417146

TSN10
Tetraspanin-10

1

11

High-throughput

0.445

High

1417155

VPS45
Vacuolar protein sorting-associated protein 45

1

10

High-throughput

0.445

High

1417159

MIC19
MICOS complex subunit MIC19

1

1

High-throughput

0.445

High

1417160

DJB12
DnaJ homolog subfamily B member 12

1

14

High-throughput

0.445

High

1417161

VAPA
Vesicle-associated membrane protein-associated protein A

1

6

High-throughput

0.445

High

1417170

PCYOX
Prenylcysteine oxidase 1

1

1

High-throughput

0.445

High

1417171

STML2
Stomatin-like protein 2, mitochondrial

1

6

High-throughput

0.445

High

1417172

BAG5
BAG family molecular chaperone regulator 5

1

10

High-throughput

0.445

High

1417173

VDAC3
Non-selective voltage-gated ion channel VDAC3

1

3

High-throughput

0.445

High

1417175

DHRS7
Dehydrogenase/reductase SDR family member 7

1

3

High-throughput

0.445

High

1417177

SAM50
Sorting and assembly machinery component 50 homolog

1

1

High-throughput

0.445

High

125602

LEG9
Galectin-9

1

20

High-throughput

0.437

High

1255380

TRI67
Tripartite motif-containing protein 67

1

4

High-throughput

0.437

High

462611

HNRPC
Heterogeneous nuclear ribonucleoproteins C1/C2

1

0

High-throughput

0.426

High

732848

GLPK
Glycerol kinase

1

0

High-throughput

0.426

High

862972

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.426

High

907757

CLCN5
H(+)/Cl(-) exchange transporter 5

1

0

High-throughput

0.426

High

912005

DGKE
Diacylglycerol kinase epsilon

1

0

High-throughput

0.426

High

963596

DAD1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit DAD1

1

0

High-throughput

0.426

High

989099

AP2B1
AP-2 complex subunit beta

1

0

High-throughput

0.426

High

1048672

SSBP
Single-stranded DNA-binding protein, mitochondrial

1

0

High-throughput

0.426

High

1092638

ECH1
Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

1

0

High-throughput

0.426

High

1104756

NNTM
NAD(P) transhydrogenase, mitochondrial

1

0

High-throughput

0.426

High

1120497

SCRB2
Lysosome membrane protein 2

1

0

High-throughput

0.426

High

1199828

AGK
Acylglycerol kinase, mitochondrial

1

0

High-throughput

0.426

High

1231463

ATLA3
Atlastin-3

1

0

High-throughput

0.426

High

1335134

KCT2
Keratinocyte-associated transmembrane protein 2

1

0

High-throughput

0.426

High

1349832

STT3B
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit STT3B

1

0

High-throughput

0.426

High

1381339

NCLN
BOS complex subunit NCLN

1

0

High-throughput

0.426

High

1382497

TM230
Transmembrane protein 230

1

0

High-throughput

0.426

High

1410654

SELS
Selenoprotein S

1

0

High-throughput

0.426

High

1413669

P4K2A
Phosphatidylinositol 4-kinase type 2-alpha

1

0

High-throughput

0.426

High

1417143

MAGT1
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit MAGT1

1

0

High-throughput

0.426

High

1417163

TM181
Transmembrane protein 181

1

0

High-throughput

0.426

High

1417164

SUCB1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.426

High

276170

NIPS2
Protein NipSnap homolog 2

1

1

High-throughput

0.407

High

280321

SC22B
Vesicle-trafficking protein SEC22b

1

5

High-throughput

0.407

High

281654

MTX2
Metaxin-2

1

1

High-throughput

0.407

High

283350

ERLN1
Erlin-1

1

2

High-throughput

0.407

High

662802

CPT2
Carnitine O-palmitoyltransferase 2, mitochondrial

1

3

High-throughput

0.407

High

888555

ACADV
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial

1

3

High-throughput

0.407

High

913392

MSH6
DNA mismatch repair protein Msh6

1

1

High-throughput

0.407

High

1042066

LMNB2
Lamin-B2

1

2

High-throughput

0.407

High

1087530

GRSF1
G-rich sequence factor 1

1

1

High-throughput

0.407

High

1091977

SEC20
Vesicle transport protein SEC20

1

2

High-throughput

0.407

High

1126358

PIGH
Phosphatidylinositol N-acetylglucosaminyltransferase subunit H

1

4

High-throughput

0.407

High

1136347

EMC2
ER membrane protein complex subunit 2

1

1

High-throughput

0.407

High

1152854

NSDHL
Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating

1

2

High-throughput

0.407

High

1322586

CP4X1
Cytochrome P450 4X1

1

5

High-throughput

0.407

High

1333699

UBAC2
Ubiquitin-associated domain-containing protein 2

1

1

High-throughput

0.407

High

1365050

UBXN4
UBX domain-containing protein 4

1

5

High-throughput

0.407

High

1386353

FAF2
FAS-associated factor 2

1

4

High-throughput

0.407

High

1393659

DDRGK
DDRGK domain-containing protein 1

1

1

High-throughput

0.407

High

1405800

TTC1
Tetratricopeptide repeat protein 1

1

17

High-throughput

0.407

High

1409585

NIPS1
Protein NipSnap homolog 1

1

1

High-throughput

0.407

High

1417148

SG196
Protein O-mannose kinase

1

1

High-throughput

0.407

High

1417149

DJC18
DnaJ homolog subfamily C member 18

1

15

High-throughput

0.407

High

1417154

RAB6B
Ras-related protein Rab-6B

1

20

High-throughput

0.407

High

1417156

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

High-throughput

0.407

High

1417157

DDX28
Probable ATP-dependent RNA helicase DDX28

1

3

High-throughput

0.407

High

1417158

DJC11
DnaJ homolog subfamily C member 11

1

10

High-throughput

0.407

High

1417167

CCG5
Voltage-dependent calcium channel gamma-5 subunit

1

2

High-throughput

0.407

High

1353592

ZN526
Zinc finger protein 526

1

0

High-throughput

0.279

Low

450269

HYEP
Epoxide hydrolase 1

1

0

High-throughput

0.232

Low

634170

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

0

High-throughput

0.232

Low

944320

TMM33
Transmembrane protein 33

1

0

High-throughput

0.232

Low

975563

SELT
Thioredoxin reductase-like selenoprotein T

1

0

High-throughput

0.232

Low

1011363

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.232

Low

1012964

RT09
Small ribosomal subunit protein uS9m

1

0

High-throughput

0.232

Low

1136159

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.232

Low

1197277

MBRL
Membralin

1

0

High-throughput

0.232

Low

1203602

ZN326
DBIRD complex subunit ZNF326

1

0

High-throughput

0.232

Low

1278670

CF120
UPF0669 protein C6orf120

1

0

High-throughput

0.232

Low

1287827

PABP2
Polyadenylate-binding protein 2

1

0

High-throughput

0.232

Low

1395622

RN170
E3 ubiquitin-protein ligase RNF170

1

0

High-throughput

0.232

Low

1406318

CGRF1
Cell growth regulator with RING finger domain protein 1

1

0

High-throughput

0.232

Low

1414662

MIC26
MICOS complex subunit MIC26

1

0

High-throughput

0.232

Low

1417140

RT26
Small ribosomal subunit protein mS26

1

0

High-throughput

0.232

Low

1417151

SFXN1
Sideroflexin-1

1

0

High-throughput

0.232

Low

1417165

FA8A1
Protein FAM8A1

1

0

High-throughput

0.232

Low

1417166

SE1L1
Protein sel-1 homolog 1

1

0

High-throughput

0.232

Low

1417169

SUN2
SUN domain-containing protein 2

1

0

High-throughput

0.232

Low

1417174

ACOT9
Acyl-coenzyme A thioesterase 9, mitochondrial

1

0

High-throughput

0.232

Low

1417176

RT23
Small ribosomal subunit protein mS23

1

0

High-throughput

0.232

Low

1417178

TIM13
Mitochondrial import inner membrane translocase subunit Tim13

1

0

High-throughput

0.232

Low

1417179

PXMP4
Peroxisomal membrane protein 4

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025