HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: LBR (Q14739)
Delta(14)-sterol reductase LBR (Delta-14-SR) (EC 1.3.1.70) (3-beta-hydroxysterol Delta (14)-reductase) (C-14 sterol reductase) (C14SR) (Integral nuclear envelope inner membrane protein) (LMN2R) (Lamin-B receptor) (Sterol C14-reductase)
Gene: LBR

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	34079125, 35271311
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005635 - nuclear envelope GO:0005637 - nuclear inner membrane GO:0016020 - membrane GO:0031965 - nuclear membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 615
+	Hs
		359945 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		LBR_HUMAN (1-615): 0: 914: 100.00
+	Mm
		821709 LMNA_MOUSE (3-580): 4.36e-63: 221: 53.37		LBR_MOUSE (1-615): 0: 907: 78.12
+	Dr
		71499 B3DKC5_DANRE (6-573): 3.64e-58: 207: 50.76		Q6DI34_DANRE (1-615): 0: 772: 51.69
+	Hs
		595458 LMNB1_HUMAN (1-586): 2.13e-71: 242: 100.00		DHCR7_HUMAN (203-615): 5.78e-169: 491: 34.00
+	Dm
		445908 LAM0_DROME (12-586): 1.5e-52: 191: 34.92		LBR_DROME (56-615): 1.16e-90: 297: 20.56