Protein: SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4 (SMARCA4) (EC 3.6.4.-) (BRG1-associated factor 190A) (BAF190A) (Protein brahma homolog 1) (SNF2-beta) (Transcription activator BRG1)

Gene: SMCA4, Smarca4
Organism: Mus musculus
Interactions: 110
UniProt ID: Q3TKT4

Gene Ontology (top 5):
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000776 - kinetochore
GO:0000785 - chromatin
GO:0000791 - euchromatin
GO:0000902 - cell morphogenesis

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1021771

SMRC1
SWI/SNF complex subunit SMARCC1

7

20

Small-scale

0.949

High

1189448

SMRC2
SWI/SNF complex subunit SMARCC2

3

20

Small-scale

0.817

High

1189434

REQU
Zinc finger protein ubi-d4

2

20

Small-scale

0.767

High

107163

F8VQD1
Protein polybromo-1

2

20

Small-scale

0.754

High

312768

BRD7
Bromodomain-containing protein 7

2

20

Small-scale

0.754

High

1189429

BRD9
Bromodomain-containing protein 9

2

20

Small-scale

0.754

High

1189442

SSXT
Protein SSXT

2

18

Small-scale

0.754

High

1189477

PHF10
PHD finger protein 10

2

20

Small-scale

0.754

High

1189485

ACL6A
Actin-like protein 6A

2

20

Small-scale

0.737

High

60006

ARI1A
AT-rich interactive domain-containing protein 1A

6

20

Small-scale

0.721

High

236728

SMCE1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1

6

20

Small-scale

0.719

High

98008

ARI1B
AT-rich interactive domain-containing protein 1B

5

20

Small-scale

0.702

High

1189483

SNF5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1

5

11

Small-scale

0.702

High

1189456

NSD2
Histone-lysine N-methyltransferase NSD2

1

20

Small-scale

0.691

High

629255

PO5F1
POU domain, class 5, transcription factor 1

3

16

High-throughput

0.667

High

1189443

TIF1B
Transcription intermediary factor 1-beta

1

16

Small-scale

0.646

High

1189454

PB1
Protein polybromo-1

1

18

Small-scale

0.646

High

1189484

MECP2
Methyl-CpG-binding protein 2

3

20

Small-scale

0.633

High

476221

RPB1
DNA-directed RNA polymerase II subunit RPB1

1

8

Small-scale

0.618

High

993092

ACTG
Actin, cytoplasmic 2

1

17

Small-scale

0.618

High

1189425

SMCA4
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4

1

17

Small-scale

0.618

High

1189440

DDX5
Probable ATP-dependent RNA helicase DDX5

1

12

Small-scale

0.618

High

1189444

MYSM1
Deubiquitinase MYSM1

1

20

Small-scale

0.618

High

1189445

SMCA2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 2

1

18

Small-scale

0.618

High

1189457

CREST
Calcium-responsive transactivator

1

20

Small-scale

0.618

High

1189465

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

13

Small-scale

0.618

High

1189468

EED
Polycomb protein EED

1

20

High-throughput

0.618

High

1189472

ACL6B
Actin-like protein 6B

1

20

Small-scale

0.618

High

1189447

SMRD3
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 3

2

20

Small-scale

0.611

High

1189435

SMRD1
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 1

2

20

Small-scale

0.594

High

59402

CHD7
Chromodomain-helicase-DNA-binding protein 7

1

16

High-throughput

0.575

High

502202

H2AZ
Histone H2A.Z

1

20

Small-scale

0.575

High

1189462

ANM5
Protein arginine N-methyltransferase 5

2

4

Small-scale

0.571

High

578327

ETS2
Protein C-ets-2

1

20

Small-scale

0.561

High

1189461

Q8C5P6
C2H2-type domain-containing protein

1

12

Small-scale

0.561

High

561640

RB
Retinoblastoma-associated protein

1

5

Small-scale

0.552

High

1189428

TF2L1
Transcription factor CP2-like protein 1

1

3

High-throughput

0.536

High

1189437

ERR2
Steroid hormone receptor ERR2

1

20

High-throughput

0.536

High

1189438

FXR1
RNA-binding protein FXR1

1

14

High-throughput

0.536

High

1189459

SALL4
Sal-like protein 4

1

10

High-throughput

0.536

High

266926

TERT
Telomerase reverse transcriptase

1

2

Small-scale

0.515

High

872983

SOX2
Transcription factor SOX-2

1

20

Small-scale

0.501

High

1189482

SRBP1
Sterol regulatory element-binding protein 1

1

20

Small-scale

0.501

High

536220

PARP1
Poly [ADP-ribose] polymerase 1

1

20

Small-scale

0.500

High

724966

SUH
Recombining binding protein suppressor of hairless

1

9

Small-scale

0.500

High

999997

HDAC2
Histone deacetylase 2

1

20

Small-scale

0.500

High

1030114

TOP2A
DNA topoisomerase 2-alpha

1

11

Small-scale

0.500

High

1032080

NOTC1
Neurogenic locus notch homolog protein 1

1

6

Small-scale

0.500

High

1189473

HDAC9
Histone deacetylase 9

1

3

Small-scale

0.500

High

107120

BICRA
BRD4-interacting chromatin-remodeling complex-associated protein

1

17

Small-scale

0.479

High

148683

HDAC1
Histone deacetylase 1

1

20

Small-scale

0.479

High

267202

KDM6A
Lysine-specific demethylase 6A

1

8

Small-scale

0.479

High

313121

HDAC3
Histone deacetylase 3

1

20

Small-scale

0.479

High

373682

MYC
Myc proto-oncogene protein

1

20

High-throughput

0.479

High

382475

P53
Cellular tumor antigen p53

1

9

Small-scale

0.479

High

558940

MYOG
Myogenin

1

13

Small-scale

0.479

High

586104

TFE2
Transcription factor E2-alpha

1

4

High-throughput

0.479

High

607334

GATA1
Erythroid transcription factor

1

20

Small-scale

0.479

High

840133

NKX25
Homeobox protein Nkx-2.5

1

20

Small-scale

0.479

High

846144

CDX2
Homeobox protein CDX-2

1

11

Small-scale

0.479

High

893667

NKX21
Homeobox protein Nkx-2.1

1

20

Small-scale

0.479

High

921355

CEBPG
CCAAT/enhancer-binding protein gamma

1

20

Small-scale

0.479

High

927748

ATX1
Ataxin-1

1

4

High-throughput

0.479

High

947428

LMBL2
Lethal(3)malignant brain tumor-like protein 2

1

4

Small-scale

0.479

High

1000124

TBX5
T-box transcription factor TBX5

1

14

Small-scale

0.479

High

1009384

C2TA
MHC class II transactivator

1

3

Small-scale

0.479

High

1021845

EYA1
Protein phosphatase EYA1

1

5

Small-scale

0.479

High

1036053

CTNB1
Catenin beta-1

1

20

Small-scale

0.479

High

1047362

NF1
Neurofibromin

1

6

Small-scale

0.479

High

1063094

GATA4
Transcription factor GATA-4

1

20

Small-scale

0.479

High

1189426

DDB1
DNA damage-binding protein 1

1

5

Small-scale

0.479

High

1189427

Q3UM65
Runt-related transcription factor

1

2

Small-scale

0.479

High

1189430

KDM6B
Lysine-specific demethylase 6B

1

6

Small-scale

0.479

High

1189431

NR1H4
Bile acid receptor

1

20

Small-scale

0.479

High

1189432

KLF4
Krueppel-like factor 4

1

20

High-throughput

0.479

High

1189436

E2F1
Transcription factor E2F1

1

8

Small-scale

0.479

High

1189439

GLI3
Transcriptional activator GLI3

1

5

Small-scale

0.479

High

1189441

SIX1
Homeobox protein SIX1

1

5

Small-scale

0.479

High

1189446

ZMIZ1
Zinc finger MIZ domain-containing protein 1

1

8

Small-scale

0.479

High

1189449

MBB1A
Myb-binding protein 1A

1

4

Small-scale

0.479

High

1189450

FACD2
Fanconi anemia group D2 protein homolog

1

5

High-throughput

0.479

High

1189451

NANOG
Homeobox protein NANOG

1

20

Small-scale

0.479

High

1189455

SRRM2
Serine/arginine repetitive matrix protein 2

1

13

Small-scale

0.479

High

1189458

KDM4A
Lysine-specific demethylase 4A

1

13

Small-scale

0.479

High

1189460

KS6A5
Ribosomal protein S6 kinase alpha-5

1

4

Small-scale

0.479

High

1189464

KDM4C
Lysine-specific demethylase 4C

1

14

Small-scale

0.479

High

1189466

SFPQ
Splicing factor, proline- and glutamine-rich

1

18

Small-scale

0.479

High

1189467

KDM4B
Lysine-specific demethylase 4B

1

14

Small-scale

0.479

High

1189469

FOXP3
Forkhead box protein P3

1

20

High-throughput

0.479

High

1189470

SMRD2
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily D member 2

1

17

Small-scale

0.479

High

1189471

NONO
Non-POU domain-containing octamer-binding protein

1

20

Small-scale

0.479

High

1189475

BCL7A
B-cell CLL/lymphoma 7 protein family member A

1

7

Small-scale

0.479

High

1189476

SSBP3
Single-stranded DNA-binding protein 3

1

8

Small-scale

0.479

High

1189479

OLIG2
Oligodendrocyte transcription factor 2

1

13

Small-scale

0.479

High

1189480

TBX21
T-box transcription factor TBX21

1

14

Small-scale

0.479

High

1189481

CAF1A
Chromatin assembly factor 1 subunit A

1

19

High-throughput

0.479

High

518511

MYOD1
Myoblast determination protein 1

1

4

Small-scale

0.445

High

706370

TBP
TATA-box-binding protein

1

3

Small-scale

0.445

High

773335

FOXA2
Hepatocyte nuclear factor 3-beta

1

20

Small-scale

0.445

High

777871

FMR1
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.445

High

1038078

PAX5
Paired box protein Pax-5

1

14

Small-scale

0.445

High

398386

CFAD
Complement factor D

1

6

High-throughput

0.437

High

595184

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

1

High-throughput

0.437

High

1189433

TRAF3
TNF receptor-associated factor 3

1

3

Small-scale

0.437

High

1189452

BACD1
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1

1

1

High-throughput

0.437

High

1189453

Q8BPK8
Fragile X messenger ribonucleoprotein 1

1

14

High-throughput

0.437

High

1189463

FNDC5
Fibronectin type III domain-containing protein 5

1

2

High-throughput

0.437

High

1189474

RN138
E3 ubiquitin-protein ligase RNF138

1

14

Small-scale

0.437

High

1189478

Q9D982
AT-rich interaction domain 2

1

20

Small-scale

0.437

High


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Last updated: 11Aug2025