Protein: TNFL9
Tumor necrosis factor ligand superfamily member 9 (4-1BB ligand) (4-1BBL)

Gene: TNFL9, TNFSF9
Organism: Homo sapiens
Interactions: 84
UniProt ID: P41273

Gene Ontology (top 5):
GO:0005102 - signaling receptor binding
GO:0005125 - cytokine activity
GO:0005164 - tumor necrosis factor receptor binding
GO:0005615 - extracellular space
GO:0005886 - plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

783235

TNR9
Tumor necrosis factor receptor superfamily member 9

4

4

Small-scale

0.895

High

352522

TNFA
Tumor necrosis factor

3

0

High-throughput

0.816

High

783242

CEA21
Carcinoembryonic antigen-related cell adhesion molecule 21

3

1

High-throughput

0.770

High

545080

PVR
Poliovirus receptor

2

0

High-throughput

0.770

High

702333

TNFL8
Tumor necrosis factor ligand superfamily member 8

2

0

High-throughput

0.770

High

783248

I27RA
Interleukin-27 receptor subunit alpha

2

0

High-throughput

0.770

High

783273

SCN3B
Sodium channel regulatory subunit beta-3

2

0

High-throughput

0.770

High

59738

KLRG2
Killer cell lectin-like receptor subfamily G member 2

2

1

High-throughput

0.726

High

121451

TR10A
Tumor necrosis factor receptor superfamily member 10A

1

4

High-throughput

0.691

High

155888

TR10C
Tumor necrosis factor receptor superfamily member 10C

1

4

High-throughput

0.691

High

560043

CTLA4
Cytotoxic T-lymphocyte protein 4

1

1

High-throughput

0.691

High

645790

CD27
CD27 antigen

1

4

High-throughput

0.691

High

685219

CEAM8
Carcinoembryonic antigen-related cell adhesion molecule 8

1

1

High-throughput

0.691

High

783238

CD226
CD226 antigen

1

1

High-throughput

0.691

High

783272

SLAF7
SLAM family member 7

1

4

High-throughput

0.691

High

588753

DPA1
HLA class II histocompatibility antigen, DP alpha 1 chain

3

2

High-throughput

0.667

High

661082

CD1B
T-cell surface glycoprotein CD1b

3

3

High-throughput

0.667

High

783241

MICA
MHC class I polypeptide-related sequence A

3

2

High-throughput

0.667

High

702200

CD70
CD70 antigen

1

0

High-throughput

0.656

High

783250

BTNL9
Butyrophilin-like protein 9

1

0

High-throughput

0.656

High

783275

CLC4A
C-type lectin domain family 4 member A

1

0

High-throughput

0.656

High

783233

FCGRN
IgG receptor FcRn large subunit p51

2

2

High-throughput

0.628

High

783259

RAE1E
Retinoic acid early transcript 1E

2

4

High-throughput

0.628

High

783278

PCDGD
Protocadherin gamma-B1

2

1

High-throughput

0.628

High

315880

VNN2
Pantetheine hydrolase VNN2

2

0

High-throughput

0.602

High

448905

MMP10
Stromelysin-2

2

0

High-throughput

0.602

High

500744

CLUS
Clusterin

2

0

High-throughput

0.602

High

702749

CADH5
Cadherin-5

2

0

High-throughput

0.602

High

783237

I13R2
Interleukin-13 receptor subunit alpha-2

2

0

High-throughput

0.602

High

783243

CC50B
Cell cycle control protein 50B

2

0

High-throughput

0.602

High

783256

SIGL1
SIGLEC family-like protein 1

2

0

High-throughput

0.602

High

530238

ICAM2
Intercellular adhesion molecule 2

2

0

High-throughput

0.585

High

783277

VSIG4
V-set and immunoglobulin domain-containing protein 4

1

0

High-throughput

0.578

High

282185

NCTR1
Natural cytotoxicity triggering receptor 1

1

1

High-throughput

0.536

High

488148

HLAC
HLA class I histocompatibility antigen, C alpha chain

1

1

High-throughput

0.536

High

519326

FCGR1
High affinity immunoglobulin gamma Fc receptor I

1

2

High-throughput

0.536

High

519405

FCERA
High affinity immunoglobulin epsilon receptor subunit alpha

1

2

High-throughput

0.536

High

783236

CAD17
Cadherin-17

1

1

High-throughput

0.536

High

783246

NR3L1
Natural cytotoxicity triggering receptor 3 ligand 1

1

1

High-throughput

0.536

High

783258

LIRB4
Leukocyte immunoglobulin-like receptor subfamily B member 4

1

2

High-throughput

0.536

High

783265

FCRL2
Fc receptor-like protein 2

1

1

High-throughput

0.536

High

783268

PD1L2
Programmed cell death 1 ligand 2

1

1

High-throughput

0.536

High

783279

PCDA9
Protocadherin alpha-9

1

1

High-throughput

0.536

High

121620

CORT
Cortistatin [Cleaved into: Cortistatin-29; Cortistatin-17]

1

0

High-throughput

0.513

High

131879

UPK2
Uroplakin-2

1

0

High-throughput

0.513

High

306767

VAMP5
Vesicle-associated membrane protein 5

1

0

High-throughput

0.513

High

437289

4F2
Amino acid transporter heavy chain SLC3A2

1

0

High-throughput

0.513

High

441818

FGF4
Fibroblast growth factor 4

1

0

High-throughput

0.513

High

454686

TACD2
Tumor-associated calcium signal transducer 2

1

0

High-throughput

0.513

High

514352

PSPC
Surfactant protein C

1

0

High-throughput

0.513

High

554282

MUC1
Mucin-1

1

0

High-throughput

0.513

High

585602

FUT1
Galactoside alpha-(1,2)-fucosyltransferase 1

1

0

High-throughput

0.513

High

713765

RYK
Tyrosine-protein kinase RYK

1

0

High-throughput

0.513

High

783240

OCLN
Occludin

1

0

High-throughput

0.513

High

783245

PLPP4
Phospholipid phosphatase 4

1

0

High-throughput

0.513

High

783247

BRID5
BRICHOS domain-containing protein 5

1

0

High-throughput

0.513

High

783251

I20RB
Interleukin-20 receptor subunit beta

1

0

High-throughput

0.513

High

783253

CA210
Type III endosome membrane protein TEMP

1

0

High-throughput

0.513

High

783255

AGRG5
Adhesion G-protein coupled receptor G5

1

0

High-throughput

0.513

High

783260

MO2R1
Cell surface glycoprotein CD200 receptor 1

1

0

High-throughput

0.513

High

783261

ASIC4
Acid-sensing ion channel 4

1

0

High-throughput

0.513

High

783262

MRAP2
Melanocortin-2 receptor accessory protein 2

1

0

High-throughput

0.513

High

783267

RARR2
Retinoic acid receptor responder protein 2

1

0

High-throughput

0.513

High

783269

TMM59
Transmembrane protein 59

1

0

High-throughput

0.513

High

783276

TNF18
Tumor necrosis factor ligand superfamily member 18

1

0

High-throughput

0.513

High

783280

ICOS
Inducible T-cell costimulator

1

0

High-throughput

0.513

High

783274

SLAF8
SLAM family member 8

1

3

High-throughput

0.489

High

205133

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

783234

TIRAP
Toll/interleukin-1 receptor domain-containing adapter protein

1

1

Small-scale

0.479

High

120138

TLR4
Toll-like receptor 4

1

0

Small-scale

0.458

High

197885

IRAK2
Interleukin-1 receptor-associated kinase-like 2

1

0

Small-scale

0.458

High

354341

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

1

High-throughput

0.445

High

58429

F234B
Protein FAM234B

2

0

High-throughput

0.328

High

783252

S39A5
Zinc transporter ZIP5

2

0

High-throughput

0.328

High

783263

RUSF1
RUS family member 1

2

0

High-throughput

0.328

High

783239

SGCA
Alpha-sarcoglycan

1

0

High-throughput

0.279

Low

783244

NHLC3
NHL repeat-containing protein 3

1

0

High-throughput

0.279

Low

783249

CP054
Transmembrane protein C16orf54

1

0

High-throughput

0.279

Low

783254

NRSN1
Neurensin-1

1

0

High-throughput

0.279

Low

783257

LRN4L
LRRN4 C-terminal-like protein

1

0

High-throughput

0.279

Low

783266

GPX7
Glutathione peroxidase 7

1

0

High-throughput

0.279

Low

783271

SACA1
Sperm acrosome membrane-associated protein 1

1

0

High-throughput

0.279

Low

783264

DDRGK
DDRGK domain-containing protein 1

1

0

High-throughput

0.249

Low

783270

SG196
Protein O-mannose kinase

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 15 Jul 2024