HitPredict

Interactor 1: LMNB1 (P20700)
Lamin-B1
Gene: LMNB1

Interactor 2: LRRK2 (Q5S007)
Leucine-rich repeat serine/threonine-protein kinase 2 (EC 2.7.11.1) (EC 3.6.5.-) (Dardarin)
Gene: LRRK2

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.68	0.50	0.585

Property	Details
Experiments	31046837, unassigned1853, 23075850
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 586 Hs			1 2527
+	Hs
		3119 A0A0S2Z428_HUMAN (4-407): 1.22e-124: 380: 22.82		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		531584 K2C5_HUMAN (4-391): 3.18e-123: 377: 23.74		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		380486 K2C6B_HUMAN (4-407): 8.91e-87: 282: 21.85		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		360019 LMNA_HUMAN (3-550): 3.87e-63: 221: 55.37		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		975674 LMNB2_HUMAN (20-586): 5.03e-61: 215: 56.22		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130283 K2C73_HUMAN (2-391): 1.07e-53: 193: 19.70		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		72923 B4DN72_HUMAN (54-390): 3.57e-50: 182: 20.18		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		1130818 V9HWE1_HUMAN (28-390): 5.22e-30: 125: 28.65		LRRK2_HUMAN (1-2527): 0: 3008: 99.72
+	Hs
		443567 VIME_HUMAN (28-390): 5.22e-30: 125: 28.65		LRRK2_HUMAN (1-2527): 0: 3008: 99.72