Protein: KCNA2
Potassium voltage-gated channel subfamily A member 2 (NGK1) (Voltage-gated K(+) channel HuKIV) (Voltage-gated potassium channel HBK5) (Voltage-gated potassium channel subunit Kv1.2)

Gene: KCNA2
Organism: Homo sapiens
Interactions: 124
UniProt ID: P16389

Gene Ontology (top 5):
GO:0001508 - action potential
GO:0005249 - voltage-gated potassium channel activity
GO:0005251 - delayed rectifier potassium channel activity
GO:0005267 - potassium channel activity
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

595043

KCAB2
Voltage-gated potassium channel subunit beta-2

5

13

Small-scale

0.912

High

595030

KCNA3
Potassium voltage-gated channel subfamily A member 3

3

15

Small-scale

0.839

High

595040

KCNA1
Potassium voltage-gated channel subfamily A member 1

2

15

Small-scale

0.768

High

595028

KCNA2
Potassium voltage-gated channel subfamily A member 2

2

14

Small-scale

0.767

High

595032

KCNA5
Potassium voltage-gated channel subfamily A member 5

2

14

Small-scale

0.754

High

595049

KCAB1
Voltage-gated potassium channel subunit beta-1

2

13

Small-scale

0.737

High

595115

KCNQ5
Potassium voltage-gated channel subfamily KQT member 5

1

14

High-throughput

0.691

High

595122

KCNG1
Voltage-gated potassium channel regulatory subunit KCNG1

1

14

High-throughput

0.691

High

595033

CAMLG
Guided entry of tail-anchored proteins factor CAMLG

4

0

High-throughput

0.674

High

595046

SRC8
Src substrate cortactin

2

6

Small-scale

0.629

High

595031

KCNA4
Potassium voltage-gated channel subfamily A member 4

1

15

Small-scale

0.618

High

595035

DLG4
Disks large homolog 4

2

20

Small-scale

0.606

High

595052

CP51A
Lanosterol 14-alpha demethylase

2

1

High-throughput

0.601

High

595063

TM214
Transmembrane protein 214

2

1

High-throughput

0.601

High

595077

CISD2
CDGSH iron-sulfur domain-containing protein 2

2

1

High-throughput

0.601

High

595093

SARAF
Store-operated calcium entry-associated regulatory factor

2

1

High-throughput

0.601

High

595104

S12A9
Solute carrier family 12 member 9

2

1

High-throughput

0.601

High

595109

REEP4
Receptor expression-enhancing protein 4

2

3

High-throughput

0.601

High

595123

AMFR
E3 ubiquitin-protein ligase AMFR

2

3

High-throughput

0.601

High

595128

TMX2
Thioredoxin-related transmembrane protein 2

2

2

High-throughput

0.601

High

248557

FADS1
Acyl-CoA

2

0

High-throughput

0.576

High

595048

ERG1
Squalene monooxygenase

2

0

High-throughput

0.576

High

595067

LCLT1
Lysocardiolipin acyltransferase 1

2

0

High-throughput

0.576

High

595085

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

2

0

High-throughput

0.576

High

595105

TM39B
Transmembrane protein 39B

2

0

High-throughput

0.576

High

595129

DHRS7
Dehydrogenase/reductase SDR family member 7

2

0

High-throughput

0.576

High

595029

PTPRA
Receptor-type tyrosine-protein phosphatase alpha

1

2

Small-scale

0.561

High

595034

RHOA
Transforming protein RhoA

1

0

Small-scale

0.549

High

73992

MYO9A
Unconventional myosin-IXa

1

5

High-throughput

0.536

High

136472

GOLI4
Golgi integral membrane protein 4

1

5

High-throughput

0.536

High

155436

C2C2L
Phospholipid transfer protein C2CD2L

1

1

High-throughput

0.536

High

161124

ABCD4
Lysosomal cobalamin transporter ABCD4

1

8

High-throughput

0.536

High

270618

ATP9A
Probable phospholipid-transporting ATPase IIA

1

1

High-throughput

0.536

High

295796

FACE1
CAAX prenyl protease 1 homolog

1

1

High-throughput

0.536

High

350348

ABHGA
Phosphatidylserine lipase ABHD16A

1

1

High-throughput

0.536

High

450211

HYEP
Epoxide hydrolase 1

1

2

High-throughput

0.536

High

595037

ARF5
ADP-ribosylation factor 5

1

1

High-throughput

0.536

High

595038

TAP1
Antigen peptide transporter 1

1

5

High-throughput

0.536

High

595039

TAP2
Antigen peptide transporter 2

1

5

High-throughput

0.536

High

595041

SRBP2
Sterol regulatory element-binding protein 2

1

2

High-throughput

0.536

High

595044

PDE3B
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3B

1

3

High-throughput

0.536

High

595054

S27A3
Long-chain fatty acid transport protein 3

1

3

High-throughput

0.536

High

595055

RNFT1
E3 ubiquitin-protein ligase RNFT1

1

3

High-throughput

0.536

High

595061

LRC8E
Volume-regulated anion channel subunit LRRC8E

1

10

High-throughput

0.536

High

595062

RETST
All-trans-retinol 13,14-reductase

1

1

High-throughput

0.536

High

595066

CC033
Protein C3orf33

1

1

High-throughput

0.536

High

595068

DHR13
Dehydrogenase/reductase SDR family member 13

1

1

High-throughput

0.536

High

595069

HACD2
Very-long-chain

1

2

High-throughput

0.536

High

595070

ADCK2
Uncharacterized aarF domain-containing protein kinase 2

1

1

High-throughput

0.536

High

595072

VRK2
Serine/threonine-protein kinase VRK2

1

5

High-throughput

0.536

High

595073

ARL17
ADP-ribosylation factor-like protein 17

1

4

High-throughput

0.536

High

595074

GHDC
GH3 domain-containing protein

1

1

High-throughput

0.536

High

595075

ABD12
Lysophosphatidylserine lipase ABHD12

1

1

High-throughput

0.536

High

595078

GOLM1
Golgi membrane protein 1

1

4

High-throughput

0.536

High

595079

UBAC2
Ubiquitin-associated domain-containing protein 2

1

1

High-throughput

0.536

High

595080

LEMD2
LEM domain-containing protein 2

1

3

High-throughput

0.536

High

595082

LRC8C
Volume-regulated anion channel subunit LRRC8C

1

10

High-throughput

0.536

High

595083

ST7L
Suppressor of tumorigenicity 7 protein-like

1

1

High-throughput

0.536

High

595084

RHBL4
Rhomboid-related protein 4

1

4

High-throughput

0.536

High

595088

NAT14
Probable N-acetyltransferase 14

1

2

High-throughput

0.536

High

595094

NGBR
Dehydrodolichyl diphosphate synthase complex subunit NUS1

1

1

High-throughput

0.536

High

595095

P121A
Nuclear envelope pore membrane protein POM 121

1

7

High-throughput

0.536

High

595098

B3GT6
Beta-1,3-galactosyltransferase 6

1

1

High-throughput

0.536

High

595103

CA043
Protein C1orf43

1

3

High-throughput

0.536

High

595108

PCX3
Pecanex-like protein 3

1

6

High-throughput

0.536

High

595110

DJC18
DnaJ homolog subfamily C member 18

1

8

High-throughput

0.536

High

595111

S38AA
Solute carrier family 38 member 10

1

1

High-throughput

0.536

High

595112

ABCB9
ABC-type oligopeptide transporter ABCB9

1

5

High-throughput

0.536

High

595113

CD320
CD320 antigen

1

6

High-throughput

0.536

High

595121

NB5R1
NADH-cytochrome b5 reductase 1

1

2

High-throughput

0.536

High

595125

VANG2
Vang-like protein 2

1

4

High-throughput

0.536

High

595126

DOLK
Dolichol kinase

1

5

High-throughput

0.536

High

595127

S27A6
Long-chain fatty acid transport protein 6

1

3

High-throughput

0.536

High

595130

ZDHC9
Palmitoyltransferase ZDHHC9

1

2

High-throughput

0.536

High

48225

TM129
E3 ubiquitin-protein ligase TM129

1

0

High-throughput

0.513

High

178606

DEGS1
Sphingolipid delta(4)-desaturase DES1

1

0

High-throughput

0.513

High

331835

GOSR1
Golgi SNAP receptor complex member 1

1

0

High-throughput

0.513

High

595042

SEC20
Vesicle transport protein SEC20

1

0

High-throughput

0.513

High

595050

SPCS2
Signal peptidase complex subunit 2

1

0

High-throughput

0.513

High

595056

PPM1L
Protein phosphatase 1L

1

0

High-throughput

0.513

High

595058

TM63B
Mechanosensitive cation channel TMEM63B

1

0

High-throughput

0.513

High

595060

LPCT4
Lysophospholipid acyltransferase LPCAT4

1

0

High-throughput

0.513

High

595087

ABHD3
Phospholipase ABHD3

1

0

High-throughput

0.513

High

595089

S35F5
Solute carrier family 35 member F5

1

0

High-throughput

0.513

High

595090

DCAKD
Dephospho-CoA kinase domain-containing protein

1

0

High-throughput

0.513

High

595096

PRR11
Proline-rich protein 11

1

0

High-throughput

0.513

High

595101

PIGQ
Phosphatidylinositol N-acetylglucosaminyltransferase subunit Q

1

0

High-throughput

0.513

High

595102

ALG12
Dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase

1

0

High-throughput

0.513

High

595117

TM38B
Trimeric intracellular cation channel type B

1

0

High-throughput

0.513

High

595118

S53A1
Solute carrier family 53 member 1

1

0

High-throughput

0.513

High

595131

SNX14
Sorting nexin-14

1

0

High-throughput

0.513

High

595100

NEUR1
Sialidase-1

1

1

Small-scale

0.501

High

49433

TM223
Transmembrane protein 223

1

1

High-throughput

0.489

High

175462

AREL1
Apoptosis-resistant E3 ubiquitin protein ligase 1

1

2

High-throughput

0.489

High

595045

UBE4A
Ubiquitin conjugation factor E4 A

1

3

High-throughput

0.489

High

595059

MARC1
Mitochondrial amidoxime-reducing component 1

1

1

High-throughput

0.489

High

595064

ZNT6
Zinc transporter 6

1

3

High-throughput

0.489

High

595065

LTMD1
LETM1 domain-containing protein 1

1

1

High-throughput

0.489

High

595081

NPL4
Nuclear protein localization protein 4 homolog

1

2

High-throughput

0.489

High

595086

UBP33
Ubiquitin carboxyl-terminal hydrolase 33

1

2

High-throughput

0.489

High

595092

MARC2
Mitochondrial amidoxime reducing component 2

1

1

High-throughput

0.489

High

595097

FACR2
Fatty acyl-CoA reductase 2

1

1

High-throughput

0.489

High

595099

DJC30
DnaJ homolog subfamily C member 30, mitochondrial

1

6

High-throughput

0.489

High

595116

ABCBA
ATP-binding cassette sub-family B member 10, mitochondrial

1

4

High-throughput

0.489

High

595124

INT6
Integrator complex subunit 6

1

1

High-throughput

0.489

High

440342

FYN
Tyrosine-protein kinase Fyn

1

9

Small-scale

0.479

High

595036

CNTP1
Contactin-associated protein 1

1

10

Small-scale

0.479

High

595047

FAK2
Protein-tyrosine kinase 2-beta

1

14

Small-scale

0.479

High

595114

RTN4
Reticulon-4

1

2

Small-scale

0.479

High

595120

CNTP2
Contactin-associated protein-like 2

1

10

Small-scale

0.479

High

325674

UBR5
E3 ubiquitin-protein ligase UBR5

1

3

High-throughput

0.445

High

595106

CARD9
Caspase recruitment domain-containing protein 9

1

5

High-throughput

0.445

High

595107

GHITM
Growth hormone-inducible transmembrane protein

1

2

High-throughput

0.445

High

595053

IPIL2
Inositol 1,4,5-trisphosphate receptor-interacting protein-like 2

1

0

High-throughput

0.426

High

595091

FAM3C
Protein FAM3C

2

0

High-throughput

0.316

High

595071

FBX11
F-box only protein 11

2

0

High-throughput

0.313

High

49622

T120B
Transmembrane protein 120B

1

0

High-throughput

0.279

Low

595051

IQCB1
IQ calmodulin-binding motif-containing protein 1

1

0

High-throughput

0.279

Low

595076

PAQR4
Progestin and adipoQ receptor family member 4

1

0

High-throughput

0.279

Low

105270

APRIO
Alternative prion protein

1

0

High-throughput

0.249

Low

341895

CEP43
Centrosomal protein 43

1

0

High-throughput

0.232

Low

595057

PR15B
Protein phosphatase 1 regulatory subunit 15B

1

0

High-throughput

0.232

Low

595119

ARMX3
Armadillo repeat-containing X-linked protein 3

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025