HitPredict

Interactor 1: ITAL (P20701)
Integrin alpha-L (CD11 antigen-like family member A) (Leukocyte adhesion glycoprotein LFA-1 alpha chain) (LFA-1A) (Leukocyte function-associated molecule 1 alpha chain) (CD antigen CD11a)
Gene: ITGAL

Interactor 2: SHRPN (Q9H0F6)
Sharpin (Shank-associated RH domain-interacting protein) (Shank-interacting protein-like 1) (hSIPL1)
Gene: SHARPIN

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.657

Property	Details
Experiments	24210817, 26600301
Identification Methods	pull down, far western blotting, affinity chromatography technology, unspecified method
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0046872 - metal ion binding
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1170 Hs			1 387
+	Hs
		506135 ITAM_HUMAN (1-1136): 0: 1055: 32.54		SHRPN_HUMAN (29-387): 5.71e-177: 499: 100.00
+	Hs
		1032205 ITAD_HUMAN (16-1157): 0: 1036: 32.31		SHRPN_HUMAN (29-387): 5.71e-177: 499: 100.00
+	Hs
		880218 ITA1_HUMAN (4-1127): 0: 984: 26.50		SHRPN_HUMAN (29-387): 5.71e-177: 499: 100.00
+	Hs
		566901 ITA2_HUMAN (19-1124): 0: 941: 25.38		SHRPN_HUMAN (29-387): 5.71e-177: 499: 100.00
+	Mm
		514519 ITA5_MOUSE (23-236): 4.09e-31: 134: 17.63		SHRPN_MOUSE (17-387): 0: 515: 73.85
+	Hs
		443096 ITA5_HUMAN (23-423): 1.31e-32: 139: 15.12		SHRPN_HUMAN (29-387): 5.71e-177: 499: 100.00
+	Hs
		439939 ITA2B_HUMAN (20-517): 9.17e-30: 130: 15.13		SHRPN_HUMAN (29-387): 5.71e-177: 499: 100.00