HitPredict

Interactor 1: HNF1A (P20823)
Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)
Gene: HNF1A

Interactor 2: HNF1B (P35680)
Hepatocyte nuclear factor 1-beta (HNF-1-beta) (HNF-1B) (Homeoprotein LFB3) (Transcription factor 2) (TCF-2) (Variant hepatic nuclear factor 1) (vHNF1)
Gene: HNF1B

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 0.60 0.713

The method score is based on:

Property Details
Experiments 10484768, 2044952, 33961781, 35140242, 36894709
Identification Methods pull down, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type direct interaction, physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000785 - chromatin
GO:0000978 - RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 - DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 - DNA binding
GO:0003700 - DNA-binding transcription factor activity
and 7 others

more...
Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 631
Hs

1 557
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Service provided by Combinatics, Japan

Last updated: 15 Jul 2024