HitPredict

Interactor 1: HNF1A (P20823)
Hepatocyte nuclear factor 1-alpha (HNF-1-alpha) (HNF-1A) (Liver-specific transcription factor LF-B1) (LFB1) (Transcription factor 1) (TCF-1)
Gene: HNF1A

Interactor 2: TLE5 (Q08117)
TLE family member 5 (Amino-terminal enhancer of split) (Amino enhancer of split) (Gp130-associated protein GAM) (Grg-5) (Groucho-related protein 5) (Protein ESP1) (Protein GRG) (TLE family member 5, transcriptional modulator)
Gene: TLE5

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.481

Property	Details
Experiments	11266540
Identification Methods	two hybrid
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 631 Hs			1 197
+	Hs
		727504 HNF1B_HUMAN (1-541): 1.27e-150: 448: 53.21		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		727505 HNF1B_HUMAN (1-541): 1.27e-150: 448: 53.21		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		727510 HNF1B_HUMAN (1-541): 1.27e-150: 448: 53.21		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Mm
		623700 PAX3_MOUSE (99-473): 1.02e-85: 278: 17.34		TLE4_MOUSE (2-191): 3.77e-112: 338: 68.59
+	Hs
		620144 PAX7_HUMAN (99-466): 9.66e-75: 249: 16.50		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		620142 PAX7_HUMAN (99-466): 9.66e-75: 249: 16.50		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		620143 PAX7_HUMAN (99-466): 9.66e-75: 249: 16.50		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		620146 PAX7_HUMAN (99-466): 9.66e-75: 249: 16.50		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		641379 PAX6_HUMAN (99-431): 2.16e-54: 192: 13.28		TLE4_HUMAN (2-191): 3.57e-112: 338: 68.59
+	Hs
		641377 PAX6_HUMAN (99-431): 2.16e-54: 192: 13.28		TLE1_HUMAN (2-197): 2.47e-111: 336: 64.50
+	Hs
		641378 PAX6_HUMAN (99-431): 2.16e-54: 192: 13.28		TLE3_HUMAN (2-197): 3.95e-105: 320: 61.50
+	Hs
		641385 PAX6_HUMAN (99-431): 2.16e-54: 192: 13.28		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993562 ARX_HUMAN (187-373): 3.43e-16: 83.9: 23.76		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Hs
		993568 PITX2_HUMAN (155-293): 7.96e-15: 77.7: 20.00		TLE5_HUMAN (1-197): 3.1e-101: 292: 100.00
+	Ce
		137665 UNC4_CAEEL (137-392): 1.19e-36: 139: 15.18		UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47
+	Ce
		105784 PAX3H_CAEEL (100-330): 7.02e-35: 135: 14.66		UNC37_CAEEL (18-160): 8.43e-43: 153: 28.47
+	Dm
		185801 PAX6_DROME (98-151): 4.92e-09: 61.6: 16.36		GROU_DROME (2-163): 3.54e-59: 198: 54.44