Interactor 1: EFNA1 (P20827)
Ephrin-A1 (EPH-related receptor tyrosine kinase ligand 1) (LERK-1) (Immediate early response protein B61) (Tumor necrosis factor alpha-induced protein 4) (TNF alpha-induced protein 4) [Cleaved into: Ephrin-A1, secreted form]
Gene: EFNA1

Interactor 2: EPHA2 (P29317)
Ephrin type-A receptor 2 (EC 2.7.10.1) (Epithelial cell kinase) (Tyrosine-protein kinase receptor ECK)
Gene: EPHA2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.92 1.00 0.961

The method score is based on:

Property Details
Experiments 36736316, 23686814, 8139691, 20505120, 22244754, 19573808, 19525919
Identification Methods affinity chromatography technology, molecular sieving, x-ray crystallography, anti tag coimmunoprecipitation
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains Ephrin~Ephrin_lbd
Common GO terms GO:0005886 - plasma membrane
GO:0007411 - axon guidance
GO:0014028 - notochord formation
GO:0016477 - cell migration
GO:0033628 - regulation of cell adhesion mediated by integrin
and 3 others

more...

Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 205
Hs

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Last updated: 15 Jul 2024