Interactor 1: IMDH1 (P20839)
Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I)
Gene: IMPDH1

Interactor 2: IMDH1 (P20839)
Inosine-5'-monophosphate dehydrogenase 1 (IMP dehydrogenase 1) (IMPD 1) (IMPDH 1) (EC 1.1.1.205) (IMPDH-I)
Gene: IMPDH1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.70 1.00 0.840

The method score is based on:

Property Details
Experiments 32296183, 23643948, unassigned1304
Identification Methods two hybrid, 3D electron microscopy, two hybrid array, two hybrid prey pooling approach, validated two hybrid
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CBS~CBS, IMPDH~IMPDH
Common GO terms GO:0000166 - nucleotide binding
GO:0003676 - nucleic acid binding
GO:0003677 - DNA binding
GO:0003723 - RNA binding
GO:0003938 - IMP dehydrogenase activity
and 10 others

more...

Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 514
Hs

1 514
+ Hs
+ Hs
+ Sc
+ Sc
+ Sc
+ Sc
+ Sc
+ Dm
+ Sp
+ Sc
+ Sc
+ Sc
+ Cj
+ Pa
+ Ec
+ Sc

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024