HitPredict

Interactor 1: FILA (P20930)
Filaggrin
Gene: FLG

Interactor 2: Q8IXN4 (Q8IXN4)
MAK protein (Male germ cell associated kinase)
Gene: MAK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	27173435
Identification Methods	tandem affinity purification
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 4061 Hs			1 457
+	Hs
		595736 FILA_HUMAN (1-4061): 0: 955: 100.00		MAK_HUMAN (1-457): 1.66e-153: 451: 96.51
+	Hs
		625483 FILA2_HUMAN (1661-4000): 4.12e-60: 233: 20.51		CDK2_HUMAN (1-296): 1.82e-140: 406: 37.12
+	Hs
		625507 HORN_HUMAN (2054-4025): 1.48e-58: 228: 17.22		CDK2_HUMAN (1-296): 1.82e-140: 406: 37.12
+	Hs
		414949 FILA2_HUMAN (1661-4000): 4.12e-60: 233: 20.51		CDK1_HUMAN (1-289): 4.73e-132: 384: 38.23
+	Hs
		414980 HORN_HUMAN (2054-4025): 1.48e-58: 228: 17.22		CDK1_HUMAN (1-289): 4.73e-132: 384: 38.23
+	Hs
		625124 S10A4_HUMAN (3-102): 8.89e-44: 157: 26.00		CDK2_HUMAN (1-296): 1.82e-140: 406: 37.12
+	Hs
		396683 S10A8_HUMAN (1-95): 1.16e-36: 136: 27.37		CDK2_HUMAN (1-296): 1.82e-140: 406: 37.12
+	Hs
		416571 S10A6_HUMAN (4-89): 2.76e-19: 87: 32.56		CDK2_HUMAN (1-296): 1.82e-140: 406: 37.12
+	Hs
		639127 S100P_HUMAN (1-95): 2.66e-45: 161: 34.74		MOK_HUMAN (1-285): 8.62e-65: 216: 40.28
+	Hs
		380766 S100B_HUMAN (1-92): 9.63e-46: 162: 34.78		CDK17_HUMAN (1-303): 1.25e-62: 213: 39.34
+	Hs
		638948 S100P_HUMAN (1-95): 2.66e-45: 161: 34.74		CDK17_HUMAN (1-303): 1.25e-62: 213: 39.34
+	Hs
		661228 S10A2_HUMAN (2-98): 9.45e-41: 148: 23.71		CDK17_HUMAN (1-303): 1.25e-62: 213: 39.34
+	Hs
		396823 S10A8_HUMAN (1-95): 1.16e-36: 136: 27.37		MOK_HUMAN (1-285): 8.62e-65: 216: 40.28