HitPredict

Interactor 1: RASA1 (P20936)
Ras GTPase-activating protein 1 (GAP) (GTPase-activating protein) (RasGAP) (Ras p21 protein activator) (p120GAP)
Gene: RASA1

Interactor 2: HD (P42858)
Huntingtin (Huntington disease protein) (HD protein) [Cleaved into: Huntingtin, myristoylated N-terminal fragment]
Gene: HTT

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.67	0.60	0.634

Property	Details
Experiments	9079622, 32814053
Identification Methods	pull down, affinity chromatography technology, two hybrid array, two hybrid pooling approach, validated two hybrid
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 1047 Hs			1 3142
+	Hs
		792090 DAPP1_HUMAN (181-277): 5.55e-12: 69.4: 31.96		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791466 GRB2_HUMAN (181-317): 1.08e-10: 64.3: 30.71		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Hs
		791541 GRAP_HUMAN (181-317): 3.7e-10: 62.8: 28.26		HD_HUMAN (1-3142): 0: 5724: 100.00
+	Mm
		103311 RASL1_MOUSE (590-722): 4.39e-12: 72.4: 17.39		G3X9H5_MOUSE (81-3142): 0: 5479: 91.19