HitPredict

Interactor 1: CD11B (P21127)
Cyclin-dependent kinase 11B (EC 2.7.11.22) (Cell division cycle 2-like protein kinase 1) (CLK-1) (Cell division protein kinase 11B) (Galactosyltransferase-associated protein kinase p58/GTA) (PITSLRE serine/threonine-protein kinase CDC2L1) (p58 CLK-1)
Gene: CDK11B

Interactor 2: CCND3 (P30281)
G1/S-specific cyclin-D3
Gene: CCND3

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.66 1.00 0.817

The method score is based on:

Property Details
Experiments 12082095, 21988832
Identification Methods two hybrid, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains Cyclin_C~Pkinase, Cyclin_N~Pkinase
Common GO terms GO:0000307 - cyclin-dependent protein kinase holoenzyme complex
GO:0004693 - cyclin-dependent protein serine/threonine kinase activity
GO:0005634 - nucleus
GO:0005737 - cytoplasm
Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 795
Hs

1 292
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ At
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs
+ Rn
+ Mm
+ Hs
+ Hs
+ Hs
+ Hs
+ Hs

Service provided by Combinatics, Japan

Last updated: 15 Jul 2024